Dietary Effects on Weight Loss and Lipid Profile in Sedentary Men

Obesity Clinical Trial

Official title:

Investigating the Effects of Negative Calorie Diet Compared With Low-Calorie Diet on Weigh Loss and Lipid Profile in Sedentary Overweight/Obese Middle-Aged and Older Men

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03082794
• Other study ID #: no Grant 4
• Status: Completed
• Phase: N/A
• First received: March 4, 2017
• Last updated: March 17, 2017
• Start date: February 20, 2011
• Est. completion date: December 27, 2012

Study information

• Verified date: March 2017
• Source: P.L.Shupik National Medical Academy of Post-Graduate Education
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of negative-calorie diet on weight loss and lipid profile, and to compare its efficiency with low-calorie diet in men.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 104
• Est. completion date: December 27, 2012
• Est. primary completion date: September 20, 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 45 Years to 75 Years

Eligibility

Inclusion Criteria:

• Non-smokers

• Weight-stable (± 2 kg, for more than one year)

• No history of regular exercise (in at least three months before the study).

Exclusion Criteria:

• History of medical disorders (CVD and other such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals, abnormality in thyroid or Electrocardiograph

• History of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.

Related Conditions & MeSH terms

• Life Style
• Lipid Metabolism Disorders
• Men
• Metabolic Diseases
• Obesity
• Overweight

Intervention

Dietary Supplement:
• NCD
Negative Calorie Diet
• LCD
Low Calorie Diet

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
P.L.Shupik National Medical Academy of Post-Graduate Education

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Weight	assessed in kg	Baseline
Primary	Total cholesterol (Total-C)	assessed in mg/dl	Baseline
Primary	High-density lipoprotein -cholesterol (HDL-C)	assessed in mg/dl	Baseline
Primary	Low-density lipoprotein -cholesterol (LDL-C)	assessed in mg/dl	Baseline
Primary	Triglycerides (TG)	assessed in mg/dl	Baseline
Secondary	Weight	assessed in kg	3-month
Secondary	Total cholesterol (Total-C)	assessed in mg/dl	3-month
Secondary	High-density lipoprotein -cholesterol (HDL-C)	assessed in mg/dl	3-month
Secondary	Low-density lipoprotein -cholesterol (LDL-C)	assessed in mg/dl	3-month