Obesity Clinical Trial
Official title:
Effect of Diabetes-specific Formulas on Glucose Metabolism and GLP-1 Secretion in Patients With Type 2 Diabetes
Diabetes-specific nutritional formulas (DSNFs) are frequently used as part of medical
nutrition therapy for patients with type 2 diabetes in order to improve glycemic control and
enhance weight reduction. The mechanism through which DSNFs improve postprandial (PP) plasma
glucose is not yet known.
The aim of this study is to compare the effects of 2 DSNFs versus oatmeal on PP plasma
glucose, serum insulin and serum active glucagon-like peptide-1 (GLP-1), serum free fatty
acids (FFA) and serum triglycerides (TG).
| Status | Completed |
| Enrollment | 25 |
| Est. completion date | October 2014 |
| Est. primary completion date | September 2014 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 20 Years to 80 Years |
| Eligibility |
Inclusion Criteria: - Patients with type 2 diabetes treated with oral diabetes medications Exclusion Criteria: - Type 1 diabetes |
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| Joslin Diabetes Center |
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Glucose area under the curve 0-240 minutes | 240 minutes | No |
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