Eating Peanuts for Health

Obesity Clinical Trial

Official title:

Peanut Consumption and Human Weight Management

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01886326
• Other study ID #: 0912008773
• Status: Completed
• Phase: N/A
• First received: June 19, 2013
• Last updated: June 21, 2013
• Start date: February 2010
• Est. completion date: May 2012

Study information

• Verified date: June 2013
• Source: Purdue University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

Evidence is accumulating that peanut consumption confers health benefits, such as reduction of cardiovascular disease risk and possibly diabetes risk (Jenkins et al., 2008; Mattes et al., 2008). However, peanuts are a high fat, energy dense food and concerns about weight gain are widespread. Although research indicates that other characteristics of peanuts offset these properties, and that peanuts may be incorporated into diets without posing a threat to weight gain (Mattes et al., 2008), concern remains among policymakers, healthcare providers, and consumers. Furthermore, worry exists that eating salted peanuts may elevate blood pressure and that eating honey-roasted peanuts make elevate blood sugar. These fears create substantial obstacles to increased peanut consumption.

Recommendations to increase peanut consumption may be made, but if they are not followed, there will be no impact on health. Additional knowledge is needed on: (1) the acceptability of peanuts consumed on a chronic basis, (2) the chronic intake of moderate levels of peanuts and body weight, and 3) the effects of peanuts on blood pressure and blood sugar. The proposed research will examine the acceptability of long-term inclusion of a single form versus varied forms of peanuts in the diet. It is expected that responses will be varied among individuals with different personality characteristics (e.g., prefer sweet versus savory foods, hedonic versus non-hedonic eaters). A better understanding of how different segments of the population choose to include peanuts in their diet and how to optimize long-term consumption should provide insights for better marketing and improved health. Furthermore, it is anticipated that eating salty peanuts will not raise blood pressure and that eating honey-roasted peanuts will not raise blood sugar. Documenting this will add credibility to the evidence that peanuts do not cause weight gain, as well as reinforce recommendations to increase peanut consumption for their health benefits.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 196
• Est. completion date: May 2012
• Est. primary completion date: May 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Between 18 and 50 years of age

• Weight stable (< 3 kg weight change within last 3 months)

• Constant habitual activity patterns (no deviation > 1x/wk at 30 min/session within last 3 months)

• Constant habitual diet patterns within last 3 months

• Willingness to eat all test foods (peanuts daily for 12 weeks)

• No allergy to foods provided in the study (peanuts)

• Not a daily peanut or tree nut consumer

• Not planning to change use of medications known to influence appetite or metabolism

• Not diabetic or hypertensive

• No history of gastrointestinal pathology

• Non-smoker for one year or more

Exclusion Criteria:

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Hyperlipidemia
• Hyperlipidemias
• Obesity
• Overweight

Intervention

Other:
• Consumption of 42 grams of peanuts daily
Consumption of the given 42 grams of peanuts daily without instructions for use (i.e. with/without meals, etc.)

Locations

Country	Name	City	State
United States	Purdue University	West Lafayette	Indiana

Sponsors (2)

Lead Sponsor	Collaborator
Purdue University	United States Agency for International Development (USAID)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Weight		2, 4, 6, 8, 10, and 12 weeks	No
Primary	Change in Blood Lipids		4, 8, and 12 weeks	No
Primary	Change in Blood Pressure		2, 4, 6, 8, 10, and 12 weeks	No
Primary	Change in Hedonics of peanut consumption	Participants will rate their liking of the sample each day using a visual analog scale.	12 weeks	No
Primary	Change in Body Composition		2, 4, 6, 8, 10, and 12 weeks	No
Primary	Change in Fasting Blood Glucose		4, 8, and 12 weeks	No
Primary	Change in Cortisol		4, 8, and 12 weeks	No
Primary	Change in Insulin		4, 8, and 12 weeks	No
Primary	Change in Pulse		2, 4, 6, 8, 10, and 12 weeks	No
Secondary	Personality Questionnaires		At baseline visit	No
Secondary	Flavor attribute liking measures		At baseline	No
Secondary	Compliance	Participants will self-report compliance to study protocol using record sheets.	12 weeks	No
Secondary	Appetitive Ratings	Collected on handheld computer	4, 8, and 12 weeks	No
Secondary	Consumption Parameters	Participants will note if peanuts were eaten as a meal or snack, at what time, and with what other foods daily.	12 weeks	No