Association of Circulating Chemerin Levels and Arterial Stiffness

Obesity Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01293929
• Other study ID #: A102065-1011-1070100
• Status: Recruiting
• Phase: N/A
• First received: February 10, 2011
• Last updated: March 3, 2011
• Start date: February 2011
• Est. completion date: March 2011

Study information

• Verified date: January 2011
• Source: Korea University
• Contact: Hye Jin Yoo
• Phone: 82226263045
• Email: deisy21[@]naver.com
• Is FDA regulated: No
• Health authority: South Korea: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Chemerin is a novel adipokine that might provide a link between chronic inflammation and obesity. Pulse wave velocity(PWV) is a useful method for examining arterial stiffness, meaning early-stage atherosclerosis. Therefore, in the present study, the investigators examined the relationship between circulating chemerin and arterial stiffness measured using PWV in obese persons.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: March 2011
• Est. primary completion date: March 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• Self referred persons for visiting routine medical check in our clinic

Exclusion Criteria:

• Malignancy

• Severe renal or hepatic disease

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Atherosclerosis
• Obesity

Locations

Country	Name	City	State
Korea, Republic of	Hye Jin Yoo	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Korea University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The difference of serum chemerin level between obese and non-obese groups	serum chemerin levels of all participants were by determined by an enzyme-linked immunosorbent assay (ELISA) kit (Biovender Laboratory Medicine Inc., Modrice, Czech Republic)	at the time of initial enrollment (4weeks)	No
Secondary	The correlation of serum chemerin levels with arterial stiffness	Arterial stiffness was measure using a Colin Waveform Analyser (model BP-203RPE II; Colin, Komaki, Japan). It was expressed as branchial ankle pulswe wave velocity (baPWV)	at the time of enrollment (4 weeks)	No