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Hormonal and Metabolic Consequences of Sleep Disorders in Young Obese Patients — SOM  

Obesity Clinical Trial

Official title:
Hormonal and Metabolic Consequences of Sleep Disorders in Young Obese Patients

Clinical Trial Summary

There is a well-documented relationship between short sleep duration and high body mass index (BMI). The mechanism linking short sleep duration and weight gain is unknown. Current studies in healthy young volunteers have shown that experimental sleep restriction is associated with dysregulation of the neuroendocrine control of appetite and with alterations in glucose metabolism. The goal of our study is to determine the metabolic and hormonal modifications induced by chronic sleep curtailment in obese adolescents and young adults and to observe if short sleep is a negative prognostic factor in their weight evolution.

Clinical Trial Description

The main purpose of the study is investigate whether the concentrations of 2 hormones that regulate appetite (leptin, ghrelin), cytokines (TNF-a, IL-6) and CRP are modified in obese adolescents and young adults who had sleep disorders in comparison to obese adolescents and young adults who sleep longer. ;

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00716222
Study type Observational
Source Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Contact Veronique VB Beauloye, PhD
Phone +3227641370
Email Veronique.Beauloye@uclouvain.be
Status Recruiting
Phase N/A
Start date May 2008
Completion date May 2009
View Details
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