Exercise Dose-Response on Features of the Metabolic Syndrome

Obesity Clinical Trial

Official title: Dose-Response Effects of Aerobic Exercise on Insulin Sensitivity and the Metabolic Syndrome

Status Completed

Clinical Trial Summary

This study investigates the degree of improvement in insulin resistance and features of the metabolic syndrome in non-diabetic overweight or obese subjects after training in a low-intensity, moderate-intensity or non-aerobic exercise program, as well as self-initiated exercise behavior after the assigned exercise program.

Clinical Trial Description

The proposed study is a randomized, open study comparing low-intensity and moderate-intensity aerobic exercise versus non-aerobic (stretching) exercise on direct measurements of insulin resistance and variables associated with the metabolic syndrome. This 6-month intervention will be followed by an additional 6-month follow-up period during which subjects will be encouraged to maintain their exercise regimen (along with their prescribed diet) but without scheduled supervision. Behavioral variables associated with adherence will be analyzed along with changes in the above physiological variables. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Insulin Resistance
• Metabolic Syndrome
• Metabolic Syndrome X
• Obesity
• Syndrome

• NCT number: NCT00687128
• Study type: Interventional
• Source: Charles Drew University of Medicine and Science
• Status: Completed
• Phase: N/A
• Start date: October 2004
• Completion date: April 2010