Clinical Trials Logo
  1. Home
  2. Other
  3. NCT04835558

Respiratory Muscle Endurance in Obesity Hypoventilation Syndrome

Obesity Hypoventilation Syndrome (OHS) Clinical Trial

Official title:
Respiratory Muscle Endurance in Obesity Hypoventilation Syndrome; Evaluation by Incremental Load Test

Clinical Trial Summary

Obesity hypoventilation syndrome (OHS) is defined as a combination of obesity [body mass index (BMI) ≥30 kg/m2], chronic daytime hypercapnia (PaCO2 >45 mm Hg), and sleep-apnea in the absence of other known causes of hypercapnia. Respiratory system compliance decreases and resistance increases in OHS. This causes increase in work of breathing and oxygen cost of breathing, which may result in respiratory muscle fatigue. Increase in respiratory workload and increase in resistance to respiration is expected to decrease in respiratory muscle endurance (RME) in subjects with OHS.

Clinical Trial Description

In the literature, studies evaluating RME in subjects with OHS are limited. No study has been found to evaluate RME using the incremental load test in subjects with OHS. Accordingly, it was aimed to evaluate and compare respiratory muscle endurance in subjects with OHS and a control group, and to determine factors associated with respiratory muscle endurance. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04835558
Study type Observational
Source Istanbul University
Contact
Status Completed
Phase
Start date February 5, 2018
Completion date January 24, 2019
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT06367686 - Detecting Systemic Carbon Dioxide Levels With a Novel Biosensor
Not yet recruiting NCT05805293 - HVNI Versus NIV In Management Of Acute Hypercapnic Respiratory Failure In OHS N/A
Recruiting NCT04884165 - Remote Monitoring to Improve Low Adherence in Non-invasive Ventilation N/A
Active, not recruiting NCT05167201 - Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom N/A
Recruiting NCT06090149 - Telemedical Assistance in Automatic Titration of Oxygen for Intensive Care Patients N/A
Recruiting NCT05448443 - Study of AD981 Versus Placebo in Obesity Hypoventilation Syndrome Phase 2
Recruiting NCT04025528 - Pathophysiology of Hypoventilation in Obesity and Effects of Bariatric Intervention
Recruiting NCT04688125 - Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy
Recruiting NCT05398068 - Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation Syndrome N/A
Withdrawn NCT04317326 - "Post-acute Pickwick Study" (Postacute-Pick-2020) N/A
Completed NCT04615078 - Study Evaluating Telemonitoring and Experimentation in Telemedicine for the Improvement of Healthcare Pathways (ETAPES Program) Compared to Standard of Care in Patients With Chronic Respiratory Failure Receiving Non-invasive Home Ventilation N/A
Completed NCT04570540 - Obesity in Sleep Medicine - Focusing on OHS Phenotypes
Not yet recruiting NCT06136533 - The Effect of Sarcopenic Obesity on Sleep in Individuals With Obesity Hypoventilation Syndrome
Withdrawn NCT01991535 - Response to NonInvasive Mechanical Ventilation According to the Breathing Pattern N/A