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Clinical Trial Summary

This study examines the interplay between genotype and phenotype and assesses if energy balance behaviors in the context of the family environment, alone or in combination, can modify behavioral and genetic predispositions to childhood obesity. The research aims to prospectively evaluate the extent to which associations of a heightened drive to eat (HDE) on 1-year changes in weight and adiposity outcomes are independent or additive to those of a genetic risk for obesity among children. In addition, the study aims to prospectively examine risk-modifying energy balance behaviors in areas of diet, physical activity, and sleep that may mitigate the detrimental impact of a HDE or high genetic risk on weight and adiposity outcomes and test whether these factors differ for HDE versus a high genetic risk of obesity on those outcomes. Lastly, the research aims to examine the impact of family-level influences in areas of family functioning and parent feeding on risk-modifying energy balance behaviors in children.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT05783765
Study type Interventional
Source University of Pennsylvania
Contact Ana Coronado
Phone (215) 746-2061
Email anacm@upenn.edu
Status Recruiting
Phase N/A
Start date July 17, 2023
Completion date October 2027

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