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Numbness clinical trials

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NCT ID: NCT06450028 Not yet recruiting - Pain, Postoperative Clinical Trials

Lidocaine Versus Bupivacaine in Orthognathic Surgery

Start date: June 10, 2024
Phase: Phase 4
Study type: Interventional

In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery. Both anesthetics are within the standard of care for dental and orthognathic procedures, but can vary in how quickly they take action and how long they last. This study will provide us with a greater understanding of how anesthetic choice affect patient outcomes, and how we can strive to make these outcomes as favorable as possible.

NCT ID: NCT06094257 Recruiting - Pain, Postoperative Clinical Trials

Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

Start date: February 9, 2022
Phase:
Study type: Observational

During breast surgery, sensory nerves are cut which may lead to reduced sensation and pain. Surgical reinnervation techniques have been developed with the aim of improving postoperative sensation by preserving the nerves and connecting them to the nipple and areola. The investigators aim to compare postoperative sensation and patient reported outcomes in patients undergoing reinnervation versus those not undergoing reinnervation to determine if there is a difference. The investigators will investigate this in patients undergoing gender-affirming mastectomy, implant-based breast reconstruction and autologous breast reconstruction. The investigators will use various tools that measure sensation quantitatively.

NCT ID: NCT03943498 Completed - Pain Clinical Trials

Fingolimod in Treating Patients With Chemotherapy-Induced Neuropathy

Start date: May 24, 2019
Phase: Early Phase 1
Study type: Interventional

This early phase I trial studies how well fingolimod works in treating patients with chemotherapy-induced nerve pain (neuropathy). Fingolimod acts by suppressing immune reactions in the brain. This study is being done to see if fingolimod can reduce neuropathy caused by chemotherapy.

NCT ID: NCT03206216 Terminated - Pain, Acute Clinical Trials

Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN

Start date: August 4, 2017
Phase: N/A
Study type: Interventional

This clinical trial studies how well Diode laser fiber type Selective Stimulator (DLss) works in predicting pain development in patients with ovarian cancer who are receiving chemotherapy. Stimulating of the pain nerve fibers in the skin with laser light stimulation may help to predict whether a patient will develop painful peripheral neuropathy, correlate with the severity of neuropathy during and after chemotherapy treatment, and may help to explain the mechanisms of chemotherapy-induced neuropathic pain (CIPN).

NCT ID: NCT02194036 Completed - Depression Clinical Trials

Learning Oriented Physiotherapy - a New Approach

LOF
Start date: August 2014
Phase: N/A
Study type: Interventional

Outpatients that suffer from different anxiety disorders may have physical ailments that negatively affect daily life functioning and quality of life. LOF is a physical therapy approach focusing on the link between bodily and mental balance and through defined, but simple movements, patients are expected to learn how to cope and reduce health complaints. This study aims to investigate the short- and longterm effect of LOF compared to other standardized psychiatric treatments given in the clinic on levels of anxiety and depression, health related function and quality of life.

NCT ID: NCT01022437 Completed - Numbness Clinical Trials

Geranium Oil and Its Components for the Relief of Numbness-OB 100

Start date: December 2008
Phase: N/A
Study type: Interventional

This study is designed to evaluate the effectiveness of geranium oil and its components in the relief of numbness and the restoration of sensations.