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Noncommunicable Diseases clinical trials

View clinical trials related to Noncommunicable Diseases.

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NCT ID: NCT06387875 Recruiting - Stroke Clinical Trials

Cohort in Qianwan New District, Ningbo

Start date: November 1, 2023
Phase:
Study type: Observational

Our objective is to carry out research on prevention and control of noncommunicable chronic diseases, and establish a risk prediction mechanism for chronic diseases to promote early detection, early diagnosis and early treatment of chronic diseases in natural population in Qianwan District of Ningbo, significantly reduce medical costs and extend population life span.

NCT ID: NCT06360029 Recruiting - Health Behavior Clinical Trials

The LvL UP Pilot Trial

Start date: April 15, 2024
Phase: N/A
Study type: Interventional

Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disability worldwide, causing major health and financial burdens. Lifestyle behaviours, including physical activity, diet, stress and emotional regulation, tobacco smoking, alcohol consumption, and sleep are important modifiable risk factors associated with the prevention and management of both NCDs and CMDs. LvL UP is a mHealth intervention aimed at preventing NCDs and CMDs in adults from multi-ethnic Southeast Asian populations (Castro et al., 2023). Building upon leading evidence- and theory-based frameworks in the areas of mental health and behaviour change, a multidisciplinary team of researchers developed LvL UP as a holistic intervention centred around three core pillars: Move More, Eat Well, Stress Less. The goal of this pilot study is to assess the feasibility of a Sequential, Multiple Assignment, Randomized Trial (SMART) aimed at (i) evaluating the effectiveness and cost-effectiveness of LvL UP and (ii) establishing the optimal blended approach in LvL UP that balances effective personalized lifestyle support with scalability. The main questions it aims to answer are: 1. What are the intervention's preliminary, short-term effects? What is the intervention's level of engagement? What is the number of dropouts? What is the percentage of missing data? What is the intervention's responder / non-responder rate after week 4? How easy was to recruit the target sample size and which channels worked best? 2. Considering the above pilot study results: What is the overall feasibility of the SMART research protocol in its current form? Are there any changes required for the main trial? This includes: recruitment approach, intervention content and delivery (app, provision of human support), and/or trial assessments (online and in-person).

NCT ID: NCT06312072 Recruiting - Clinical trials for Chronic Kidney Diseases

Understanding Risk Factors for Progressive Chronic Kidney Disease in Malawi

Start date: February 14, 2024
Phase:
Study type: Observational

Worldwide, the number of people living with long-term health conditions, including chronic kidney disease (CKD), is increasing. CKD is usually asymptomatic in early stages but can progress to advanced disease, including kidney failure, causing significant morbidity and mortality. In low-income countries of sub-Saharan Africa, including Malawi, treatments for kidney failure are not yet widely available and are prohibitively expensive . It is therefore vital to: (a) Prevent development of CKD in the first place (b) Detect CKD earlier so that more cost-effective treatments can be given to slow progression. There is little evidence on factors that drive CKD progression in Malawi, or on interventions that may be cost-effective for improving detection and slowing disease progression in this setting. This PhD will address these knowledge gaps, through the following aims: 1) Determine the mortality associated with CKD, and the risk factors driving its development and progression in Malawian adults 2) Investigate the impacts of different models for integrating screening and prevention strategies for CKD and its risk factors into health services for other long-term conditions in low- and middle-income countries 3) With patients, carers, healthcare workers and policy makers, evaluate the feasibility and acceptability of different potential models for integrating CKD screening and prevention strategies into health services for high-risk patient groups in Malawi

NCT ID: NCT06311162 Recruiting - Asthma in Children Clinical Trials

Early Life Intervention in Pediatrics Supported by E-health - SMOKE

ELIPSE-II
Start date: May 7, 2024
Phase: N/A
Study type: Interventional

Unrestricted parental smoking habits are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of non-communicable diseases (NCDs). Exposure to secondhand tobacco smoke in early life contributes to the development of specific NCDs in children, i.e. asthma. Early preventive measures to improve lifestyle behavior in parents are therefore of utmost importance. The aim of ELIPSE-II is to assess whether an eHealth application intervention for parents is feasible and efficacious in lowering levels of urinary cotinine as a measure of second-hand smoke exposure in their children .

NCT ID: NCT06208345 Recruiting - Childhood Obesity Clinical Trials

Early Life Intervention in Pediatrics Supported by E-health

ELIPSE-I
Start date: February 16, 2024
Phase: N/A
Study type: Interventional

Childhood obesity in early life contributes to the development of specific NCDs, i.e. adult obesity. Unhealthy diet and low level of physical activity are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of NCDs. Early preventive measures to improve lifestyle behavior are of utmost importance. The aim of ELIPSE-I is to assess whether an eHealth application intervention for parents is feasible and efficacious in lowering total energy intake/total energy expenditure (TEI/TEE) ratio in their children with BMI >97 centile (ELIPSE-I).

NCT ID: NCT06077565 Recruiting - Clinical trials for Non Communicable Diseases

General-health-promotion-approach to Promoting Healthier Lives

Start date: January 5, 2024
Phase: N/A
Study type: Interventional

Aim To examine the effectiveness of a general-health-promotion-approach to help ED attendees change their health-risk behaviours and lead healthier lives. Hypotheses to be tested The investigators hypothesise that compared with those in the control group, the participants in the intervention group will experience significantly greater success in changing their health-risk behaviours and will have a better health-related quality of life at 12 months follow-up.

NCT ID: NCT05950919 Recruiting - HIV Clinical Trials

Effects of a Package of Evidence-based Interventions and Implementation Strategies Based on WHO PEN for People Living With HIV and Cardio-metabolic Conditions in Lusaka, Zambia

TASKPEN UH3
Start date: May 30, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effects of a multi-level intervention known as "TASKPEN," adapted from the World Health Organization (WHO) Package of Essential Noncommunicable Disease Interventions (WHO-PEN) for the Zambian public health system, on clinical and implementation outcomes for persons living with HIV (PLHIV) with co-morbid cardio-metabolic conditions in Lusaka, Zambia.

NCT ID: NCT05907226 Recruiting - Clinical trials for Health Risk Behaviors

Compare Smokers' Appraisal of Proposed Plain Packs and Existing Cigarette Packs

Start date: June 4, 2023
Phase:
Study type: Observational

2 Objectives 1. To explore the noticeability of pictorial health warnings and perceptions of attractiveness and harmfulness towards plain cigarette packets and existing cigarette packets with 85% pictorial warnings in current smokers; 2. to compare the differences in perceptions of packaging in current smokers with different characteristics (i.e. by sex, age, the consumption level of cigarettes, nicotine dependence levels, and types of tobacco used for polytobacco product users); 3. to evaluate the effectiveness in reducing smoking consumption and promoting quit attempts; and 4. to assess the support for the legislation of plain packaging.

NCT ID: NCT05790395 Recruiting - Clinical trials for Non Communicable Diseases

Prevention of NCDs Through Screening and Educating Individuals on Health-risk Behaviours in the Community

Start date: July 13, 2023
Phase: N/A
Study type: Interventional

Aim: to prevent NCDs by screening and educating individuals in the community on health-risk behaviours. Specifically, we will use a mobile health and a brief self-determination theory-based intervention in helping individual change their health-risk behaviours. Hypotheses to be tested: compared with those in the control group, the participants in the intervention group will experience significantly greater success in modifying their health-risk behaviours and will have a better health-related quality of life at 12 months follow-up. Objectives 1. To screen individuals for health-risk behaviours and identify risk factors that may contribute to NCDs 2. To educate individuals on the importance of engaging in healthy lifestyles 3. To develop a training programme - "Train the Trainers' Toolkit", with the goal to train student nurses (Years 2 to 5) as health ambassadors to implement the project on a long-term basis.

NCT ID: NCT05750953 Recruiting - Heart Failure Clinical Trials

Nurse-assisted Intervention "eHealth@ Hospital -2-home"

Ehealth@H2H
Start date: May 5, 2023
Phase: N/A
Study type: Interventional

A randomized controlled trial with non-communicable disease patients from two medical hospitals in Norway will be recruited prior to hospital discharge. The intervention group will participate in a 42-day nurse-assisted eHealth intervention "eHealth@ Hospital-2-Home". The intervention includes monitoring the patient's vital signs, self-reports of symptoms, health and well-being, communication between the patients and a Nurse Navigator in the hospital, and access to information about illness and health resources.