Proton Boost for Locally Advanced HEAD AND NECK TUMORS

Status Completed

Clinical Trial Summary

The aim of this research project is to test the local response and the acute toxicity (which can be observed within 90 days).

Clinical Trial Description

Local response and acute toxicity are primary endpoints of the trial. At CNAO a proton boost is delivered on the PTV1rx (area at high risk of relapse) up to at least 70 Gy [RBE] in 2-3 Gy [RBE] per fractions for 8-15 total fractions.

PTV2 rx (area at low or intermediate risk of relapse) will be irradiated with photon IMRT up to a total dose of 50-60 Gy [RBE].

Secondary endpoints of the trial are local control, relapse free survival, overall survival, tumor specific survival, intermediate and long term toxicity. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03183271
Study type	Interventional
Source	CNAO National Center of Oncological Hadrontherapy
Contact
Status	Completed
Phase	N/A
Start date	July 16, 2012
Completion date	September 30, 2016

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