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Nephrolithiasis clinical trials

View clinical trials related to Nephrolithiasis.

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NCT ID: NCT03584373 Completed - Nephrolithiasis Clinical Trials

Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.

PO-NOA
Start date: July 27, 2018
Phase: Phase 3
Study type: Interventional

There are two options for postoperative pain management: opioid and non-opioid analgesia. Pain outcomes will be compared in patients undergoing ureteroscopy and percutaneous nephrolithotomy by randomly administering opioid and non-opioid analgesia.

NCT ID: NCT03567421 Completed - Stone, Kidney Clinical Trials

Ureteral Stenting After Ureteroscopy for Stone Treatment, A Global Perspective on Indications and Outcomes

Start date: June 7, 2018
Phase:
Study type: Observational [Patient Registry]

Background: The exit strategy after ureteroscopy for stone treatment remains a topic for discussion. Current EAU guidelines on urolithiasis state that postoperative stenting is indicated in patients at increased risk of postoperative complications. Stenting is not considered necessary in all other cases, and after uncomplicated procedures. Objective: To analyse the postoperative ureteral stenting strategy in clinical practice looking at the indication, type of stents used and the duration of stenting after ureteroscopy for stone treatment. Furthermore, the investigators will examine in what setting the stents are being removed postoperatively. Study design: This study is a prospective, observational, international, multicentre registry study executed by uCARE. Study population: All patients >18 years with a ureter or renal stone who are planned for ureteroscopic treatment by semi-rigid and/or flexible ureteroscopy are eligible for this study.

NCT ID: NCT03549611 Withdrawn - Pain, Postoperative Clinical Trials

Pre-induction Analgesia: Multimodel Regimen vs Aceteminophen for Post Ureteroscopy Pain

MMPITR
Start date: August 1, 2018
Phase: Phase 4
Study type: Interventional

Adult patients with kidney stones undergoing surgical intervention with ureteroscopy with laser lithotripsy will be randomized to receive one of two different regimens of oral medications administered prior to induction of general anesthesia. Postoperatively, patients will receive automated daily text messages to assess pain and opioid consumption and subsequently determine which which treatment regimen is superior.

NCT ID: NCT03503539 Completed - Kidney Stone Clinical Trials

Are the Stone Density and Location Useful Parameters for Small Kidney Stones?

Start date: April 2016
Phase: N/A
Study type: Interventional

The investigators aimed to evaluate whether these parameters could be guides for us in the selection of RIRS or Mini-PNL procedures in kidney stones that are smaller than 2 cm. The patients that have kidney stones smaller than two cm and be planned to undergo surgery were randomized into 2 groups prospectively. RIRS was performed in the RIRS group using a 7.5-F fiberoptic flexible ureterorenoscope while Mini-PCNL group was dilated up to 16.5F and mini-PCNL was performed with 12F nephroscopy. Preoperative characteristics, operative and postoperative results were compared in two groups. Thereafter, intra and intergroup comparisons were made to determine the effects of HU value, indicating the stone density, higher or less than 677 and the stone location on stone-free rates.

NCT ID: NCT03461536 Completed - Nephrolithiasis Clinical Trials

Ultrasound First Clinical Decision Support for Suspected Nephrolithiasis

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

This is a randomized trial to determine the effectiveness of a clinical decision support tool on image ordering for patients with suspected nephrolithiasis. Patients who present with acute unilateral flank or abdominal pain in whom emergency department providers suspect nephrolithiasis will receive either the clinical decision support tool or no tool (usual care).

NCT ID: NCT03454139 Completed - Nephrolithiasis Clinical Trials

Subcostal TAP Block For Percutaneous Nephrolithotomy

Start date: October 2015
Phase: N/A
Study type: Interventional

Percutaneous nephrolithotomy (PCNL) is a minimally- invasive procedure for removing kidney stones. The small incision of PCNL is performed medially from the posterior axillary line according to stones location. Despite the small skin incision patients suffer from postoperative pain due to visceral pain and intercostal nerve injury. The aim of this study is to evaluate the perioperative analgesic effect of subcostal transversus abdominis plane (TAP) block performed prior to PCNL procedure. Primary outcome of our study was Morphine consumption at 48th hour after the surgery. Secondary outcomes were perioperative fentanyl consumption; postoperative Verbal Analog Scale and additional analgesic drug requirement.

NCT ID: NCT03388060 Completed - Urologic Diseases Clinical Trials

(SWL) Versus (ODT) Versus Combined SWL And ODT For Radiolucent Stone

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

compare the efficacy of of ultrasound guided SWL versus dissolution therapy versus combined SWL and dissolution therapy in management of 1 - 2.5 cm renal stones.

NCT ID: NCT03379922 Completed - Nephrolithiasis Clinical Trials

Strategies to Maximise Patient Comfort During ESWL

Start date: March 27, 2017
Phase: N/A
Study type: Interventional

Extracorporeal shockwave lithotripsy is an outpatient treatment for patients with intrarenal calculi. Standard of care involves offering oral analgesia prior to commencing the treatment. Most patients do not take the offered analgesia after the initial treatment. It has been suggested that distraction techniques may be equivalent to oral analgesia in improving tolerability of extracorporeal shockwave lithotripsy treatment. The use of distraction techniques also removes the potential side effects of mediation administration.

NCT ID: NCT03373617 Completed - Renal Stone Clinical Trials

The Effect of Anesthesia Type on RIRS

Start date: December 13, 2017
Phase:
Study type: Observational [Patient Registry]

Retrograde intrarenal surgery (RIRS) with flexible ureteroscopy is based on video monitoring of urinary tract during operation. Therefore, shaking vision on monitor can bother surgeons and make them tired. This can lead in tissue injury from lasing. The purpose of this study is to investigate the stability of monitoring of surgical field which is assessed by surgeon.

NCT ID: NCT03349099 Completed - Urolithiasis Clinical Trials

Impact Ureteral Sheath Design During Ureteroscopy

Start date: June 27, 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether one of two ureteral access sheaths is safer for patients undergoing ureteroscopy. Both sheaths are FDA approved devices and commercially available. The investigators will compare the ability of sheaths to access the kidney through the ureter and will compare damage done to the ureter after completion of the procedure. Access sheaths are standard of care for this procedure; this study seeks to optimize outcomes for patients. Patients undergoing ureteroscopy who do not have ureteral stents in place and who have not had an ipsilateral procedure within 90 days will be recruited and consented.