Clinical Trials Logo

Nephrolithiasis clinical trials

View clinical trials related to Nephrolithiasis.

Filter by:

NCT ID: NCT01077284 Completed - Kidney Stones Clinical Trials

Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones

Start date: February 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy of febuxostat, once daily (QD), compared to allopurinol or placebo in patients with excessive amounts of uric acid in their urine and who have recently had kidney stones.

NCT ID: NCT01022060 Completed - Clinical trials for Recurrent Calcic Urolithiasis

Renalof in the Dissolution of Renal Calculi in Patients With Recurrent Calcic Lithiasis

Start date: November 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether Renalof administration promotes partial or total dissolution of urinary calculi and improves physicochemical parameters and metabolic activity in patients with recurrent calcic urolithiasis. The duration of this double-blind placebo controlled phase 3 clinical trial will be 12 weeks. The estimated number of patients to be recruited and randomized for the study is 110. Ultrasonographic and humoral parameters will be assessed every 4 weeks.

NCT ID: NCT00952315 Completed - Kidney Stones Clinical Trials

Trial Comparing Three Different Devices for Kidney Stone Removal During Percutaneous Surgery

Start date: August 2009
Phase: N/A
Study type: Interventional

The investigators plan to compare three different devices that are used to break up large kidney stones during surgery for removal to see if one is faster or more efficient than the others.

NCT ID: NCT00893282 Completed - Kidney Stones Clinical Trials

Clinical Evaluation of BackStop in Patients Undergoing Intraureteric Stone Lithotripsy

Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to evaluate BackStop, a polymer-based device that is intended to be used during ureteroscopic lithotripsy to prevent retrograde stone migration. It is a water soluble polymer with reverse thermosensitive properties; the polymer exists as a liquid at low temperature (below 17 C) and rapidly transitions to a high viscosity gel at body temperature (i.e. in the ureter). BackStop is injected above the stones in the ureter and is intended to prevent retrograde migration of stones during ureteroscopic lithotripsy. Upon completion of the lithotripsy procedure, BackStop dissolves naturally or by irrigation. The study hypothesis is that a greater proportion of patients will experience no retropulsion of a kidney stone when BackStop is used versus no anti-retropulsion device when undergoing intracorporeal lithotripsy.

NCT ID: NCT00873054 Completed - Kidney Stones Clinical Trials

Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy

Start date: October 2008
Phase: N/A
Study type: Observational

The investigators main hypothesis is that the stone free rate will be much higher (95%) in patients treated with PCNL than patients treated with ESWL where stone free rate is (60%) to determine which treatment is safe and prevent less stone recurrence.

NCT ID: NCT00857090 Completed - Kidney Stones Clinical Trials

Pharmacokinetic, Safety and Efficacy Study of OMS201 in Subjects Undergoing Retrograde Ureteroscopic Removal of Upper Urinary Tract Stones

Start date: March 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The objectives of the study are to assess the systemic exposure, safety and efficacy of three concentrations of OMS201 in subjects undergoing retrograde ureteroscopic removal of upper urinary tract stones.

NCT ID: NCT00784472 Completed - Kidney Stones Clinical Trials

Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL

Start date: December 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the effect of oxynorm versus morphine after operation for kidney stone (PCNL). In addition the relationship between pain symptoms and referred sensory and trophic changes will be examined in the patients before and after the operation.Finally a blood sample is analysed to investigate pharmaca-genetics.

NCT ID: NCT00765128 Completed - Kidney Stones Clinical Trials

Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy

Start date: October 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having percutaneous nephrolithotomy for kidney stone disease.

NCT ID: NCT00762424 Completed - Kidney Stone Clinical Trials

Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis

Flowmax
Start date: June 2007
Phase: N/A
Study type: Interventional

Tamsulosin (Flowmax)is approved by the FDA for the treatment for enlarged prostate. Several studies regarding the use of Tamsulosin for the treatment of lower kidney stones have been carried out in the non-Emergency Department setting. This study will compare Tamsulosin 0.4 mg with placebo in regards to rate and time of stone passing and will also look at amount of pain. The purpose of this study is to compare the usefulness of Tamsulosin versus placebo on time to stone passage and pain relief in Emergency Department patients with kidney stones.

NCT ID: NCT00600405 Completed - Nephrolithiasis Clinical Trials

The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients

Start date: August 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the efficacy of the α-adrenergic antagonist tamsulosin in the treatment of adult emergency department (ED) patients with ureteral colic secondary to lower ureteral calculus. We hypothesize that there will be no difference in outcomes for subjects treated with and without tamsulosin.