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Necrosis clinical trials

View clinical trials related to Necrosis.

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NCT ID: NCT05596188 Recruiting - Prostate Cancer Clinical Trials

Anxiety Before Non-cardiac Surgery in Adults

Start date: November 10, 2022
Phase:
Study type: Observational [Patient Registry]

Adult patients undergoing elective non-cardiac surgery were enrolled. Anxiety before the operation was evaluated by The State Anxiety Inventory (S-AI). Logistics regression would be used for identifying the independent factors of preoperative anxiety and prediction model would be established.

NCT ID: NCT05593523 Recruiting - Burn Wound Clinical Trials

Fluorescence-based Detection of Inflammation and Necrosis to Inform Surgical Decision-making and Enhance Outcomes

Start date: March 9, 2023
Phase:
Study type: Observational

This study investigates fluorescence image-guided surgery to allow precise identification of necrotic tissue both preoperatively and intraoperatively in burn patients. Furthermore, it uses a multi-model approach to elucidate the localization of ICG in inflammation and necrosis to determine how this novel use of a well-known fluorescence marker can be optimized to aid in surgical decision making. This proposal will provide the necessary data to support the design of a larger clinical trial to study the feasibility and efficacy of this technology to improve the precision of necrosis detection and removal and improve wound healing outcomes. Up to 100 participants will be on study for up to approximately 24 days.

NCT ID: NCT05592145 Completed - Clinical trials for Post-Op Complication

Quantifying the Venous Congestion Curve of a Tissue Oximetry Device

Start date: November 10, 2022
Phase: N/A
Study type: Interventional

The purpose of this research study is to measure rate of decline and pattern of tissue oxygenation using the device, ViOptix T.Ox. ViOptix probes will be secured to the arm and hand. The recording process on the ViOptix machine will begin and obtain baseline StO2 levels for 5 minutes. After 5 minutes, a blood pressure cuff will be inflated on one arm. This blood pressure cuff will be left inflated for 10-20 minutes. Every 2 minutes a pulse check or doppler exam will be performed at your wrist. Last, the cuff will be deflated and the you will be free to leave the study room.

NCT ID: NCT05587244 Enrolling by invitation - Clinical trials for Rheumatoid Arthritis

G7 Freedom Constrained Vivacit-E Liners

Start date: May 8, 2023
Phase: N/A
Study type: Interventional

The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of the G7 Freedom Constrained Vivacit-E Acetabular Liners in primary and revision total hip arthroplasty.

NCT ID: NCT05582421 Not yet recruiting - Clinical trials for Apical Periodontitis

Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.

Start date: December 2022
Phase: Early Phase 1
Study type: Interventional

the aim of this study is to compare the effect of using Diclofenac Sodium Versus Calcium Hydroxide as Intracanal medication on intensity of postoperative pain, bacterial load reduction after root canal preparation and periapical matrix metalloproteinase 9 level (MMP-9) post-instrumentation and pre-obturation in teeth with necrotic pulp

NCT ID: NCT05574088 Completed - Pain, Postoperative Clinical Trials

Comparison of Postoperative Pain With or Without Apical Patency Technique in Asymptomatic Necrotic Teeth

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Apical patency is a technique in which the apical portion of the canal is maintained free of soft tissue remnants and dentinal debris by recapitulation with a small #10k file through the apical foramen. The purpose of this study is to evaluate the association between apical patency and postoperative pain in teeth with asymptomatic necrotic pulp among patients attending the Peshawar Dental College and Hospital. This single center, double blinded prospective RCT study will be conducted in Peshawar Dental College and Hospital. The inclusion criteria will be mature maxillary and mandibular molars and premolars diagnosed with asymptomatic necrotic pulp and apical periodontitis among 18-60 aged male and female patients, whereas pregnant patients, individuals with previously accessed teeth, and those having positive history of analgesic use within past 3 days will be excluded from the study. A total of 60 patients, after an informed consent will be randomly allocated one of the two groups i.e., apical patency (AP)(n = 30) and the non-apical patency (NAP) (n = 30) in a ratio (1:1).After administering localanaesthesia, root canal preparation will be completed using ProTaper rotary instruments.A size 10 K-filewas carried 1 mm beyond the working length in the patency groupused as a patency file.Patients will be asked to mark their pain intensity on 0-10 scale (NRS)for 7 days. Data will be analyzed using ChiSquare test, Student t-test, Kolmogorov-Smirnov test.

NCT ID: NCT05571371 Not yet recruiting - Clinical trials for MCP-2: Monocyte Chemo-attractant Protein-2

Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure

seizure
Start date: October 2022
Phase:
Study type: Observational

1. Evaluation of the role of TRAIL and MCP-2 in differentiation between epileptic seizure and psychogenic non-epileptic seizure. 2. Possible role to predict the prognosis of patients with epileptic seizure.

NCT ID: NCT05548972 Enrolling by invitation - Clinical trials for Rheumatoid Arthritis

G7 Dual Mobility With Vivacit-E or Longevity PMCF

Start date: March 20, 2023
Phase: N/A
Study type: Interventional

This study is a global, multi-center, prospective, non-controlled, non-randomized, post-market clinical follow-up study. The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of the G7 Dual Mobility Acetabular System when used with the Vivacit-E or Longevity polyethylene hip bearing and instrumentation in primary total and revision (total) hip arthroplasty

NCT ID: NCT05548257 Not yet recruiting - Clinical trials for Femoral Head Necrosis

Mortality and Related Risk Factors After Hip Arthroplasty

Start date: September 20, 2022
Phase:
Study type: Observational

The patients who underwent hip arthroplasty in our hospital from January 2017 to December 2020 were reviewed. The perioperative data were collected, and then the mortality was calculated and the risk factors were analyzed.

NCT ID: NCT05532475 Recruiting - Clinical trials for Retinal Vein Occlusion

Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein Occlusion

Start date: March 12, 2022
Phase:
Study type: Observational

To assess the levels of TNF- α in vitreous samples of patients with retinal vein occlusion prior to administration of intravitreal anti-VEGF and compare them to levels in vitreous samples of normal subjects so as to investigate the association of vitreous tumor necrosis factor with the pathogenesis of retinal vein occlusion.