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Nausea clinical trials

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NCT ID: NCT06046027 Completed - Clinical trials for Postoperative Nausea and Vomiting

P6 Acupressure Band for Prevention of Postoperative Nausea and Vomiting in Children

Start date: January 31, 2020
Phase: N/A
Study type: Interventional

Nausea and vomiting after surgery are one of the most common side effects of general anaesthesia. Pressure at P6 acupuncture point around wrist area using acupressure band has been proven to reduce nausea and vomiting in adult. We would like to see if this acupressure band can reduce nausea and vomiting in children after surgery. Prior to operation, we will apply an elastic band at the P6 acupoint on your child's both hands. Your child will undergo anaesthesia as per usual and surgery as planned, with the elastic band onboard. Upon completion of surgery, your child will be required to wear the band and should not be removed. Your child will be monitored for up to 24 hours for episodes of nausea and vomiting. If so, rescue antivomit medication will be given. After 24 hours, we will record your level of satisfaction with the regimen provided

NCT ID: NCT06045364 Active, not recruiting - Nausea and Vomiting Clinical Trials

Effect of Glycopyrrolate on Nausea and Vomiting After ERCP Operation

Start date: October 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims to determine the role of Glycopyrrolate in preventing postoperative nausea and vomiting of ERCP.

NCT ID: NCT06043336 Completed - Clinical trials for Postoperative Nausea and Vomiting

Palonosetron vs Combination of Granisetron and Dexamethasone in Preventing PONV in Laparoscopic Cholecystectomy.

Start date: May 10, 2018
Phase: Phase 4
Study type: Interventional

This is a prospective, randomized, double-blinded study comparing the post-operative nausea vomiting (PONV) profile following administration of intraoperative palonosetron alone and the combination of granisetron and dexamethasone in moderate to high-risk patients undergoing elective laparoscopic cholecystectomy. Patients aged 18-65 years with American Society of Anesthesiologists physical status I or II were randomized into two groups. Group A received 1 ml of intravenous (IV) 0.9% saline after intubation and IV palonosetron 0.075 mg at the end of operation. Group B received IV dexamethasone 4 mg after intubation and IV granisetron 1 mg at the end of surgery. The occurrence of PONV and the need for rescue antiemetics were assessed at 30 minutes, 4, 24 and 48 hours post-anesthesia. A complete response towards the study drugs was considered when patients did not experience PONV and did not require rescue antiemetics. The side effects of the study drugs were evaluated. Patient satisfaction with the anti-emetics administered was assessed. These parameters were compared between Group A and Group B: the occurrence of PONV, the need of rescue antiemetics, the side effects of the study drugs and patient satisfaction with the anti-emetics administered.

NCT ID: NCT06040411 Completed - Pain Clinical Trials

The Effect of Acupressure on Preoperative Anxiety and Postoperative Pain and Nausea-Vomiting

Acupress
Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The study was conducted in the ENT Clinic of Mersin Şehir Training and Research Hospital between June 1 and December 1, 2021, with a total of 60 adult patients, 30 in the study group and 30 in the control group, who met the inclusion and exclusion criteria.

NCT ID: NCT06022705 Recruiting - Clinical trials for Nausea, Postoperative

Evaluation of the Effect of APFEL Risk Score and Fasting Periods on Postoperative Nausea and/or Vomiting

Start date: August 28, 2023
Phase:
Study type: Observational [Patient Registry]

This study, it is aimed to determine the effect of Apfel risk score and fasting times on postoperative nausea and vomiting (PONV).

NCT ID: NCT06017284 Recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic Cancer

PTCA199-5
Start date: November 1, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of thalidomide on improving the quality of life for metastatic pancreatic cancer patients receiving gemcitabine and nab-paclitaxel chemotherapy.

NCT ID: NCT06017167 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Start date: September 15, 2022
Phase: Phase 2
Study type: Interventional

The aim of the study is to compare antiemetic effects between dexmedetomidine and ondansteron in the first group versus dexamethasone and ondansteron in the second group. The primary outcome in this study is incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy. The secondary outcomes are: - The severity of post operative nausea and vomiting. - Use of rescue antiemetic drugs. - Postoperative pain and sedation.

NCT ID: NCT06009211 Not yet recruiting - Nausea Clinical Trials

Impact of Aromatherapy on Nausea in Hospitalized Children Undergoing Rehabilitation

Start date: May 1, 2024
Phase:
Study type: Observational

Children, ages 8 - 17, will be enrolled in a research study about the impact of aromatherapy on nausea in the pediatric rehabilitation unit.

NCT ID: NCT06008262 Enrolling by invitation - Clinical trials for Postoperative Nausea and Vomiting

Cold Application Effects on Nausea and Vomiting After Laparoscopic Cholecystectomy

Start date: July 3, 2023
Phase: N/A
Study type: Interventional

This clinical trial aims to test the effect of cold application on postoperative nausea and vomiting.

NCT ID: NCT05998317 Completed - Postoperative Pain Clinical Trials

Dexamethasone at Night vs at Induction on PONV After Laparoscopic Cholecystectomy

Start date: October 8, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

Since the peak effect of the dexamethasone is delayed to 12-16 hours after iv administration, we designed this study to investigate the effect of administering dexamethasone at-night before surgery versus at-induction (the standard timing) in prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy. A pilot randomized controlled study (60 cases) will be started to explore the potential difference, ensure correct and rigorous data collection, and calculate the sample size for a larger pragmatic trial.