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Myocardial Ischemia clinical trials

View clinical trials related to Myocardial Ischemia.

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NCT ID: NCT05125367 Completed - Clinical trials for Multivessel Coronary Artery Disease

Ten-Year Outcomes of Randomized Comparison of Coronary Artery Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease

BEST Extended
Start date: May 1, 2022
Phase:
Study type: Observational

The primary objective of the BEST extended 10Y follow-up study is to compare the safety and effectiveness of coronary stent implantation using everolimus-eluting balloon-expandable stents with bypass grafting for the treatment of multivessel coronary artery disease at minimum of 10 years follow-up.

NCT ID: NCT05109715 Completed - Myocardial Ischemia Clinical Trials

The Effect of Mechanical Ventilation on the Occurrence of Myocardial Ischemia: a Pilot Study

VENTMICS
Start date: January 24, 2022
Phase: N/A
Study type: Interventional

The goal of the proposed pilot study is to determine which method can detect myocardial ischemia at the predefined timepoints during endo-CABG. Additionally, the investigators want to examine the influence of mechanical ventilation on the occurrence of myocardial ischemia in patients undergoing endo-CABG.

NCT ID: NCT05093790 Completed - Clinical trials for Coronary Artery Disease

A Study to Evaluate BMS-986141 Added on to Aspirin or Ticagrelor or the Combination, on Thrombus Formation in a Thrombosis Chamber Model in Participants With Stable Coronary Artery Disease and Healthy Participants

Start date: March 25, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the effectiveness, safety and tolerability of BMS-986141 added on to aspirin or ticagrelor or the combination on thrombus formation in both healthy participants and participants with stable coronary artery disease.

NCT ID: NCT05088291 Completed - Clinical trials for Coronary Heart Disease

Application of a New X-ray Protective Device in Coronary Interventional Therapy

Start date: September 30, 2021
Phase:
Study type: Observational

This is a multi-center, prospective and controlled clinical trial which will enroll 200 coronary arteriography or percutaneous coronary intervention with 2-4 interventional cardiologist. The interventional cardiologist performed 100 interventional procedures using either a new protective device (NPD) or a traditional lead clothing (TLC). The cumulative dose outside the NPD or TLC and the first operator at each height (110cm, 90cm, 50cm, 10cm) was measured. The main indicators of the study are the average X-ray shielding efficiency of the NPD and the TLC at four different heights. The investigators will record all operation information in this study.

NCT ID: NCT05071495 Completed - Clinical trials for Coronary Artery Disease

TeleDiet Study: The Impact of Dietary Education and Counseling With a Smartphone Application on Secondary Prevention of Coronary Artery Disease

Start date: March 17, 2021
Phase: N/A
Study type: Interventional

Digital cardiology is gaining power in the field of preventive cardiology recently, and several trials have already shown good results of dietary therapy with digital cardiology. However, there has been no reports that showed effect of dietary counseling through digital cardiology for secondary prevention of coronary artery disease. TeleDiet study investigates the impact of dietary therapy with a smartphone application on the content of meals and metabolic parameters for patients with coronary artery disease.

NCT ID: NCT05051904 Completed - Clinical trials for Coronary Artery Disease

A Study Based on Japanese Medical Records That Looks at Bleeding Events in People With Atrial Fibrillation and Coronary Artery Disease Who Start Taking Either Dabigatran, Rivaroxaban, or Warfarin

Start date: May 17, 2022
Phase:
Study type: Observational

The study aims to evaluate the safety and effectiveness comparisons between warfarin, dabigatran, and rivaroxaban in routine clinical practice among Japanese non-valvular atrial fibrillation (NVAF) patients with concomitant coronary artery disease (CAD).

NCT ID: NCT05039567 Completed - Clinical trials for Coronary Artery Disease

Effect of an Optimal Heart Team Protocol on Decision-making Stability

Start date: January 4, 2022
Phase: N/A
Study type: Interventional

This study is aimed to evaluate the effect of the optimal heart team implementation protocol on the stability of decision-making for patients with complex coronary artery disease.

NCT ID: NCT05032937 Completed - Clinical trials for Coronary Heart Disease

the Accuracy and Safety of Coronary Artery Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle

Start date: October 13, 2021
Phase: Phase 1
Study type: Interventional

This is a single-center, prospective, controlled and diagnostic clinical trial which will enroll 30 patients scheduled for coronary angiography in China.Patients will receive contrast-enhanced cardiac magnetic resonance with polysaccharide superparamagnetic iron oxide nanoparticle before percutaneous coronary angiography.In order to evaluate the safety of polysaccharide superparamagnetic iron oxide nanoparticle, patients will detect iron levels in peripheral and tissue before and after the examination.The main indicators of the study are the degree of coronary artery stenosis and the stability of coronary atherosclerotic plaque assessed by contrast-enhanced cardiac magnetic resonance with polysaccharide superparamagnetic iron oxide nanoparticle.

NCT ID: NCT05022498 Completed - Sleep Clinical Trials

Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to examine the reproducibility of postprandial coronary heart disease (CHD) risk marker and sleep responses to acute exercise bouts and to quantify the magnitude of individual variability in responses using a replicated crossover design. Healthy, recreationally active men will complete two identical rest control and two identical exercise (60 min at 60% maximum oxygen uptake) conditions in randomised sequences. Fasting and postprandial venous blood samples, arterial blood pressure and arterial stiffness measurements will be taken at pre-determined intervals, and sleep duration and quality will be assessed. Reproducibility and individual variability will be examined using bivariate correlations and linear mixed modelling.

NCT ID: NCT05015270 Completed - Clinical trials for Coronary Artery Disease

Correlation of Biomarkers With the Presence and Severity of Coronary Artery Disease

PREDICTION-NJ
Start date: July 21, 2021
Phase:
Study type: Observational

The development of coronary artery disease is multifactorial. Peripheral blood biomarkers paly an important role in the prediction of coronary artery disease. However, the identification of those biomarkers and their correlation with the presence and severity of coronary artery disease are unclear. The present study aims to identify the differentially expressed biomarkers from peripheral blood between normal population and patients with different disease burden confirmed by coronary angiography, and to analyze the correlation of those biomarkers with the severity of coronary artery disease. Finally, the prediction of biomarkers for clinical events.