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Association Between Genetic Variant Scores and P2Y12 Inhibitor Effects — CARES1  

Myocardial Infarction Clinical Trial

Official title:
Correlation Between Bleeding Complication and Treatment Failure on P2Y12 Inhibitors and Its Predictions Based on Cipherome's Pharmacogenomic Technology

Clinical Trial Summary

The goal of this study is to predict and prevent adverse drug events by investigating the impact of genetic variants, demographics, and environmental factors in subjects status post myocardial infarction and percutaneous coronary insertion who have experienced adverse drug events while on P2Y12 inhibitors.

Clinical Trial Description

The goal of this study it to validate Cipherome's drug safety score (DSS) in its predictive accuracy for severe adverse drug reactions (ADRs). The DSS is calculated on a scale of 0 to 1, with preliminary studies demonstrating that scores below 0.3 correlated with a higher chance of an ADR and scores above 0.7 correlated with a lower chance of an ADR. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04580602
Study type Observational
Source Cipherome, Inc.
Contact
Status Completed
Phase
Start date October 7, 2020
Completion date June 9, 2022
View Details
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