Venous Function in Cardiovascular Disease Patients

Myocardial Infarction Clinical Trial

Official title:

Venous Function in Cardiovascular Disease Patients; The Neglected Part of Circulatory Regulation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01474408
• Other study ID #: 2011/760
• Status: Completed
• Phase: N/A
• First received: November 4, 2011
• Last updated: February 13, 2017
• Start date: November 2011
• Est. completion date: November 2012

Study information

• Verified date: February 2017
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The primary aim is to determine the acute effect of two different training interventions on venous plasticity in patients with myocardial infarction (MI), revascularization or coronary artery graft surgery compared to age-matched healthy subjects.

Description:

Compare the effect of 4 x 4 minutes at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate and moderate continuous exercise at 70 % of peak heart rate on venous function.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: November 2012
• Est. primary completion date: November 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• myocardial infraction (MI)

• revascularization (PCI)

• coronary artery bypass graft surgery (CABG)

Exclusion Criteria:

• unstable angina pectoris

• uncontrolled hypertension

• orthopedic and/or neurological limitations

• participation in other studies

• MI (closer than 4 weeks)

Related Conditions & MeSH terms

• Cardiovascular Diseases
• Infarction
• Myocardial Infarction

Intervention

Behavioral:
• interval training day 1

• Moderate exercise day 2

• Control day 3

Locations

Country	Name	City	State
Norway	Institutt for Sirkulasjon og Bildetechnikk, NTNU	Trondheim

Sponsors (1)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Leinan IM, Aamot IL, Støylen A, Karlsen T, Wisløff U. Upper arm venous compliance and fitness in stable coronary artery disease patients and healthy controls. Clin Physiol Funct Imaging. 2015 Dec 15. doi: 10.1111/cpf.12324. [Epub ahead of print] — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Venous Compliance change	Measured by echocardiography	48 hours