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Muscle Spasticity clinical trials

View clinical trials related to Muscle Spasticity.

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NCT ID: NCT04858646 Completed - Clinical trials for Spastic Cerebral Palsy

Aerobic Exercises and Gross Motor Function in Spastic Cerebral Palsy

Start date: January 15, 2019
Phase: N/A
Study type: Interventional

The aim of this research is to find the effects of aerobic exercise on gross motor function in cerebral palsy patients. Quasai experimental study done at Noor Zainab Rehabilitation center, Lahore. The sample size was 34. The subjects were divided in two groups, 17 subjects with aerobic exercise 17 children with conventional treatment. Sampling technique applied was purposive non probability sampling. Only 7-12 years individuals with GMFCS level I- III were included. Tools used in the study were Gross motor function measure (GMFM-66 and 88) .Data was be analyzed through SPSS 21.

NCT ID: NCT04851756 Completed - Spasticity, Muscle Clinical Trials

Effects of CRet Associated With Functional Massage (F.M) on Gait and Functionality in Post-stroke Spasticity

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the immediate effects of CRet associated to Functional Massage (F.M) in terms of gait and functionality after stroke

NCT ID: NCT04839939 Completed - Gait Clinical Trials

Efficacy of Combination Taping Technique vs Ankle Foot Orthosis on Improving Gait Parameters in Cerebral Palsy

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Gait in children with spastic CP is often characterized by abnormal gait kinematics as knee flexion and equines foot which associated with such gait deviations, an elevated walking energy cost is often observed which may contribute to activity limitations. The ability to maintain proper joint alignment of the lower extremity, and control the position of the foot in standing and walking is a critical treatment objective for gait in children with cerebral palsy. Lower extremity orthoses, such as ankle-foot orthoses (AFOs) are widely recommended in children with spastic cerebral palsy to prevent the development or progression of this deformity and to improve the dynamic efficiency of the child's gait. The use of Kinesio taping in pediatric rehabilitation becomes increasingly popular in recent years. Recent systematic reviews reported moderate evidence that Kinesiology taping is a useful adjunct to physiotherapy intervention in higher functioning children with CP. Combination tapings is a technique first introduced by Kenzo Kase, in which Kinesio taping is coupled with the rigid athletic tape to maximize the treatment benefits. This approach remains briefly addressed in the literature with no prior studies has examined the effects of combination tapings in the CP pediatric population. Hypothesis: there is no difference between the effect of combining tapings and ankle-foot orthosis on spatiotemporal gait parameters in spastic cerebral palsied

NCT ID: NCT04826900 Completed - Spastic Clinical Trials

Wearable Robotic System and Robotic Mirror Therapy in Spastic Hemiplegia Post Botulinum Toxin Injection

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this project is to examine and compare the immediate and long-term effects of combined Botulinum toxin type A(BoNT-A) injection with wearable robotic hand system (RT) and Robotic mirror therapy (RMT) in patients with spastic hemiplegic stroke.

NCT ID: NCT04824768 Completed - Spasticity, Muscle Clinical Trials

Effect of Tecar in Addition of Functional Massage in Post-stroke Spasticity

Tecar
Start date: May 20, 2021
Phase: N/A
Study type: Interventional

Spasticity is due to an abnormal processing of a normal input from muscle spindles in the spinal cord.

NCT ID: NCT04792229 Completed - Spastic Diplegia Clinical Trials

Effects Of Whole Body Vibration On Lower Extremity With Diplegic Spastic Cerebral Palsy

Start date: October 16, 2020
Phase: N/A
Study type: Interventional

This study will help to determine the beneficial effects of high frequency vibration on children with diplegic cerebral palsy in improving balance ,spasticity, strength of lower limb and quality of life and a comparison between the effect of simple conventional treatment and conventional management with the usage of vibrational therapy in cp patients.

NCT ID: NCT04789629 Completed - Cerebral Palsy Clinical Trials

Effect of Low Level Laser Therapy on Hamstring Muscle Tightness and Calf Muscle Spasticity in Cerebral Palsy Children.

cp
Start date: December 1, 2020
Phase: N/A
Study type: Interventional

Background :Spasticity is a motor disorder in children with cerebral palsy (CP) Cp is a non progress lesion in unmature brain lead to a group of chronic disorders that affect movement and posture development, may be accompanied by epilepsy, secondary musculoskeletal problems, deformaties and disturbances of sensation, perception, cognition, communication, and behavior Few studies demonstrate effectiveness of laser therapies in spasticity in cp. Methodology : This study is randomize control trail aimes to evaluate the effect of low-level laser therapy (LLLT) on the spasticity of hamstring and calf muscle in children with CP over 12 session of intermittent laser exposures. Muscle tone , gross motor function, rang of motion (rom ) and poplital angle will evaluate before and after laser irradiation in 30 children with CP both geneder aged between two to six years old diaplegic clidren , exclusion children who take botox or done surgery . Muscles will irradiated with low-intensity diode laser pulses of 808-nm wavelength three times per week over one month follow up for one month.

NCT ID: NCT04780191 Completed - Stroke Clinical Trials

Investigation of Treatment Using the MyoRegulator® Device in Patients With Spasticity in the Lower Limb Due to Stroke

SPAST
Start date: July 19, 2018
Phase: N/A
Study type: Interventional

This is a single center, randomized, double-blind (patient and evaluator), sham-controlled study. The main objectives of this study are to evaluate the performance and safety of the MyoRegulator® device in active versus sham treated stroke patients with lower-limb spasticity after 5 consecutive days of treatment.

NCT ID: NCT04770363 Completed - Stroke, Acute Clinical Trials

Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.

NCT ID: NCT04768166 Completed - Clinical trials for Hereditary Spastic Paraparesis

Testing Miglustat Administration in Subjects With Spastic Paraplegia 11

TreatSPG11
Start date: June 15, 2021
Phase: Phase 2
Study type: Interventional

Hereditary spastic paraparesis type 11 (SPG11) is caused by mutations in the SPG11 gene that produces spatacsin, a protein involved in lysosomal function. Studies performed in skin cells (fibroblasts) from SPG11 patients, mice and zebrafish models of the disease showed that the material accumulated in the lysosomes is made of glycosphingolipids (GSL). Miglustat is a drug that inhibits an enzyme called glucosylceramide synthetase (GCS) which is used for the production of GSL. Miglustat, therefore, helps to delay the production of GSL. This study aims to collect preliminary data on the safety of miglustat on the SPG11 disease and to assess biomarkers.