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Muscle Spasticity clinical trials

View clinical trials related to Muscle Spasticity.

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NCT ID: NCT05251025 Completed - Cerebral Palsy Clinical Trials

Myofascial Release and Sustained Stretching in Spastic CP Children

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

The aim of this research was to find and compare the effects of Myofascial Release Technique and Passive Sustained Stretching on Hamstrings Flexibility in Children with Spastic Cerebral Palsy.

NCT ID: NCT05242679 Completed - Stroke Clinical Trials

Effect of Myofascial Release With Tennis Ball on Spasticity and Motor Functions

Start date: November 21, 2016
Phase: N/A
Study type: Interventional

Impaired motor function and upper extremity spasticity are common concerns in patients after stroke. It is essential to plan therapeutic techniques to recover from the stroke. The objective of this study was to investigate the effects of myofascial release with the tennis ball on spasticity and motor functions of the upper extremity in patients with chronic stroke.

NCT ID: NCT05231538 Completed - Cerebral Palsy Clinical Trials

Neurodevelopmental Therapy for Spastic Cerebral Palsy

NDT
Start date: June 17, 2021
Phase: N/A
Study type: Interventional

This study was conducted to find out the Effects of Neurodevelopment therapy (a rehabilitative program designed by Bobath) on Gross Motor Function and Postural Control in Children with Spastic Cerebral Palsy. To investigate either there was a significant difference between the effects of neurodevelopment therapy and routine physical therapy on gross motor function and postural control in children with Spastic Cerebral Palsy.

NCT ID: NCT05206240 Completed - Stroke, Ischemic Clinical Trials

Extracorporeal Shock Wave Therapy and Assessment Strategy Through a Novel Gait Analysis Tool for Post-stroke Spasticity

Start date: March 1, 2021
Phase:
Study type: Observational

The aim of this study is to objectively evaluate the effectiveness of radial extracorporeal shock wave therapy (rESWT) and conventional physical therapy program on the gait pattern through a new gait analysis system which encompasses spatiotemporal and kinematic parameters and to correlate the findings with the clinical evaluation.

NCT ID: NCT05196737 Completed - Stroke Clinical Trials

DDN in Stroke--COBRE

CDN
Start date: March 7, 2022
Phase: N/A
Study type: Interventional

The study team is recruiting 20 adults with spasticity due to chronic stroke for a 7 day study over 2 weeks. In people with chronic stroke, one of the most common and disabling problems is spasticity (increased muscle tone or muscle stiffness). The purpose of this research study is to examine effects of dry needling on the nervous system (pathways between the muscle, spinal cord, and brain) in people with spasticity due to chronic stroke. Dry needling is a procedure in which a thin, stainless steel needle is inserted into the skin to produce a muscle twitch response. It is intended to release a knot in the muscle and relieve pain. The total study duration is 7 visits over 2 weeks. There will be 4 visits the first week, and 3 visits the second week. The first visit will take about 1.5 hours, during which study staff will determine the best placement of electrodes and create a cast of the participant's leg to aid them in quickly placing the electrodes on the remainder of the visits. The second and fifth visits will last about 3.5 hours, and all other visits will last about 1.5 hours. Dry needling will take place on the fifth visit only. During each visit the participant will be asked to participate in examinations of reflexes (muscle responses to non-invasive nerve stimulation) and leg function.

NCT ID: NCT05183100 Completed - Stroke Clinical Trials

Effects of Neurodynamics on Lower Extremity Spasticity - a Study in Chronic Stroke

Start date: October 18, 2021
Phase: N/A
Study type: Interventional

Post-stroke spasticity in the lower extremity affects balance and gait, leading to decreased mobility and functional independence. Therefore, effective intervention for reducing spasticity is crucial in stroke rehabilitation. Recently, neurodynamics, though originally designed for pain management in orthopedic patients, has also been applied for treating spasticity in patients with neurological disorders. However, previous studies focused mainly on treating the upper extremity spasticity, but not on lower extremity spasticity, and not on possible neurophysiological changes. The present study aims to investigate the immediate effects of neurodynamics in reducing lower limb spasticity and neurophysiological changes in people with chronic stroke.

NCT ID: NCT05174403 Completed - Clinical trials for Spastic Paraplegia Type 5A, Recessive

Imaging Biomarkers in Spastic Paraplegia Type 5

SPIMA
Start date: January 28, 2022
Phase:
Study type: Observational

This is a research study aiming to identify imaging biomarkers in patients diagnosed with spastic paraplegia type 5 (SPG5)

NCT ID: NCT05169775 Completed - Clinical trials for Upper Limb Spasticity (ULS)

A Single Centre, Prospective, Observational Study to Assess the Use of the Rehabilitation Tool, GripAble, in Patients With Upper Limb Spasticity Receiving Botulinum Toxin-A (BoNT-A) in the United Kingdom (UK).

Start date: March 2, 2022
Phase:
Study type: Observational

The purpose of this study is to explore how a rehabilitation tool (GripAble) could be used to monitor the effect of BoNT-A during an injection cycle and understand its potential value as a home rehabilitation tool in routine practice.

NCT ID: NCT05164003 Completed - Muscle Spasticity Clinical Trials

CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase1)

Start date: July 17, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and pharmacodynamic of CORETOX® in the treatment of post-stroke upper limb spasticity

NCT ID: NCT05126693 Completed - Clinical trials for Spastic Cerebral Palsy

Short Term Follow-up of a Botulinum Toxin Intervention in Children With Spastic Cerebral Palsy

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

This study investigates the effect of integrated Botulinum Neurotoxin A (BoNT) treatment on morphologic muscle and tendon properties, spasticity, joint stiffness, joint range of motion, muscle strength, gait and gross motor function. The integrated BoNT treatment combines BoNT-injections with serial casting and intensive physical therapy, as previously described by Molenaers et al. The current study will include 30 children who are clinically scheduled for BoNT treatment in the medial gastrocnemius and/or the semitendinosus muscle in the intervention group and 30 children in a control group who will receive usual care within a time span of 3 months.