View clinical trials related to Muscle Hypertonia.
Filter by:To assess the safety and tolerability of single and multiple doses of MTR-601 in normal healthy volunteers under fed and fasted conditions. To evaluate the plasma and urine pharmacokinetics (PK) of MTR-601. To evaluate the pharmacodynamic (PD) effects of MTR-601 on muscle strength and muscle accumulation of MTR-601 by muscle biopsy and other potential mechanistic, predictive and PD markers of MTR-601.
In chronic hemiparesis, abnormal antagonist muscle activation in the paretic lower limb contributes to impair ambulation capacities. A biased estimate of antagonist muscle activation when using surface bipolar EMG compared with high-density (HD) EMG has been previously reported in healthy subjects. The present study compares muscles cocontraction at the paretic ankle estimated with a pair of and multi-channel surface EMG.
The aim is to assess the influence of asymmetric training on the locomotor system in sweep rowers. To analyse possible changes objectively, the axial position of the hull will be assessed using Moiré topography, and the symmetry of foot loading will be monitored with a pedobarograph. Furthermore, the Visual Analog scale and Cluster of Laslett will determine whether an asymmetric load can provoke pain in the lumbar region or cause a blockage in the SI joint. In the experimental study, there will be three different groups of participants. Selected sweep rowers will make the first study group. The second group will consist of scull rowers, and the last control group will consist of people with no experience with rowing. The selected participants will undergo the first measurement at the turn of the spring and summer seasons when intensive preparation for rowing competitions begins, in which sweep rowers train mainly on water and asymmetrically. The measurement results in the three groups will be further compared with each other to evaluate whether statistically significant differences can be found.
The study will determinate the influence of four selected physiotherapeutic procedures on the pain intensity, the bioelectrical activity of the masseter muscle, and the range of mandibular mobility in patients with TMDs (temporomandibular joint dysfunction).
The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic Upper Airway Obstruction (HUAO).
Multi-center, three-arm, randomized, evaluator-blinded study of electrical muscle stimulation (EMS) and/or 1064 nm diode laser, pulsed electromagnetic field (PEMF) and vacuum assisted radio frequency (RF) using the Venus Bliss Max for fat reduction, body contouring and aesthetic improvement.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
The myotonometric assessment is becoming popular and important in athletic population. It is mentioned an alternate method than expensive methods, and it is easy and reliable assessment. Still there is not enough information of mechanical characteristics in athletic population and ankle mobility. Most clinicians or trainers can use this results and technique for enhancing performance, rehabilitation or prevention
The goal of this study is to evaluate a top-rated Prague rehabilitation school´s method. Part of Prague rehabilitation school is called Mojžíšová Method, which is mainly used for the treatment of back pain and woman´s non-structural sterility. This method offers an original, innovative way, how to mobilize 1.- 7. costo-sternal joints. This type of mobilization is very effective, fast and safe and probably widely used only in the Czech Republic. Mojžíšová method uses the excentric force of patients pectoral muscle, passive stretch and shoulder joint internal rotation. According to Mojžíšová, If one of the ribs joints has dysfunction (limited range of motion), there can be found higher sensitivity of this joint, certain muscle reflex spasm, hypersensitive zones and joint dysfunction. Probably the last study evaluating this method was made in the 1990s.
Evaluation of HIFEM treatments for strengthening and toning of arms, lower limbs and oblique muscles.