Bright Light Therapy as Possible Treatment Option for MS-Fatigue

Status Recruiting

Clinical Trial Summary

This study aims to investigate the effect of a 2-week trial of bright light therapy (BLT, 10.000 lx) on fatigue in multiple sclerosis (MS) patients. In this randomised placebo-controlled trial, the effect of bright light therapy will be compared to dim red light. MS-fatigue is quantified by patients using a visual analogue scale (VAS) and activity levels, subjective and objective sleep parameters and daytime sleepiness are measured.

Clinical Trial Description

Materials and methods: - visual analogue scale (4x/day for 6 weeks; measuring fatigue) - wrist actigraphy (6 weeks) - sleep diaries (6 weeks) - polysomnography (2x) - multiple sleep latency test (2x) - 4 subtests of the TAP (Testbatterie zur Aufmerksamkeitsprüfung; Alertness, Vigilance, Go/No-Go, Split Attention) - questionnaires (Fatigue Severity Scale, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Beck Depression Inventory, Beck Anxiety Inventory, Modified Fatigue Impact Scale, Morningness-Eveningness Questionnaire) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04681586
Study type	Interventional
Source	Medical University of Vienna
Contact	Stefan Seidel, MD
Phone	0043 1 40 400 34280
Email	stefan.seidel@meduniwien.ac.at
Status	Recruiting
Phase	N/A
Start date	December 1, 2019
Completion date	January 2022

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