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Clinical Trial Summary

Personal identity is composed of multiple facets of the self that are constructed and nourished through memories of past experiences (i.e., autobiographical memory) and the imagination of events that may occur in the future (i.e., future thinking) . While our previous work has shown that people with relapsing-remitting multiple sclerosis (pwRRMS) have autobiographical memory and future thought disorders, their impact on personal identity has not yet been explored. Based on a cognitive and clinical neuropsychology approach, this research project aims to better understand the cognitive mechanisms involved in the relationship between identity, autobiographical memory and future thinking in pwRRMS. We will examine the extent to which pwRRMS manage to maintain and reshape their identity through life experiences, with a particular interest in the potential integration of the disease as a facet of their identity. In addition, we will explore the positive and/or negative consequences of disease-related identity changes on emotional well-being and quality of life, as well as their links with the duration and severity of the disease. Overall, this research project will contribute to identify new therapeutic levers that can be used for the development of adapted and personalized care.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05648292
Study type Observational [Patient Registry]
Source Centre d'Investigation Clinique et Technologique 805
Contact Alexandra Ernst, PhD
Phone +33628496210
Email aernst@univ-paris8.fr
Status Recruiting
Phase
Start date December 7, 2022
Completion date June 7, 2025

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