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Moyamoya Disease clinical trials

View clinical trials related to Moyamoya Disease.

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NCT ID: NCT03162588 Completed - Ischemic Stroke Clinical Trials

Multiple Burrhole Therapy With Erythropoietin for Unstable Moyamoya

Start date: May 1, 2010
Phase: Phase 1/Phase 2
Study type: Interventional

In this study, the investigators aim to evaluate the indirect revascularization outcomes of a new combination therapy of multiple burrhole procedure with promotion of arteriogenesis by intravenous (IV) erythropoietin (EPO) pretreatment on Moyamoya patients with acute neurological presentation, and outline the clinical and vascular factors associated with revascularization through the burrholes.

NCT ID: NCT03072914 Completed - Moyamoya Disease Clinical Trials

Effects of Remote Ischemic Preconditioning With Postconditioning on Neurologic Outcome

Start date: March 7, 2017
Phase: N/A
Study type: Interventional

In the present study, we evaluated whether RIPC with RIPostC reduce the major neurocomplication in patients undergoing STA-MCA anastomosis.

NCT ID: NCT02982135 Recruiting - Moyamoya Disease Clinical Trials

Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease

Start date: January 2016
Phase: N/A
Study type: Interventional

The investigators conducted a prospective multi-center study assessing the effect of direct bypass and indrect bypass in treatment of hemorrhagic moyamoya disease.

NCT ID: NCT02510586 Not yet recruiting - Moyamoya Disease Clinical Trials

Sevoflurane and Hyperperfusion Syndrome

Start date: August 2015
Phase: N/A
Study type: Interventional

The aim of the present study is to evaluate the effect of sevoflurane postconditioning on the incidence of postoperative hyperperfusion syndrome following revascularization surgery in moyamoya patients.

NCT ID: NCT02434302 Completed - Moyamoya Clinical Trials

Characteristics and Outcomes of Childhood Moyamoya in the UK

Start date: August 2014
Phase:
Study type: Observational

This is a study to ascertain the number of children with moyamoya in the UK, their presenting features, clinical course and outcomes.

NCT ID: NCT02319980 Active, not recruiting - Stroke Clinical Trials

The Adult Hemorrhagic Moyamoya Surgery Study

AHMSS
Start date: May 2015
Phase: Phase 3
Study type: Interventional

The aim of this study is to investigate whether extracranial-intracranial(EC-IC) bypass surgery could prevent rebleeding and improve neurological function in adult moyamoya with hemorrhagic onset.

NCT ID: NCT02305407 Recruiting - Moyamoya Disease Clinical Trials

Neurocognitive and Radiological Assessments in Adult Moyamoya Undergoing Surgery

NRAAMUS
Start date: March 2016
Phase: N/A
Study type: Interventional

Adult patients with moyamoya disease (MMD) are reported to suffer from considerable impairment of executive function/attention. Although reduced cerebrovascular reserve (CVR) in frontal areas has been detected by perfusion MRI and then confirmed to be associated with executive dysfunction in adult MMD, the structural and functional changes is still unclear with progression of executive dysfunction. Furthermore, it is very important to study the association between the neurocognitive and radiological improvement after surgical revascularization, so as to help detecting cerebral regions which are involved in executive deterioration or improvement after surgery. Then the investigators can determine whether these regions can be used as indicators to decide rational therapeutic schedule and timing of adult MMD with executive dysfunction. Thus the aim of this study is to primarily find out the neuropsychological and radiological correlates in adult MMD, and then to quantitatively evaluate the effectiveness of surgical revascularization in prevention of executive dysfunction in adult MMD.

NCT ID: NCT02090010 Unknown status - Clinical trials for Intracranial Aneurysm

Subclavian Vein catheterization_Seldinger Vs Modified Seldinger

MS
Start date: April 2014
Phase: N/A
Study type: Interventional

Seldinger technique is a minimally invasive technique in which the practitioner accesses the target vessel with a small bore needle, then dilates to the size required for the catheter. Contrarily, modified Seldinger technique(guiding sheath-over-the-needle technique) use needle that is covered with guiding sheath. Both technique is widely used in central venous catheterization, however, few researches have been investigated to compare success rate or complications of both methods.

NCT ID: NCT02074111 Recruiting - Moyamoya Disease Clinical Trials

Moyamoya Disease Biomarkers in Patients With Intracranial Atherosclerotic Stroke

Start date: January 2014
Phase: N/A
Study type: Observational

The aim of this study is to investigate the proportion of patients with moyamoya disease among the patients who were diagnosed as having intracranial atherosclerotic stroke. To do this, biomarkers (gene and imaging) for moyamoya disease are tested and follow up angiography are performed during follow up (in selected patients).

NCT ID: NCT01419275 Completed - Clinical trials for Cerebrovascular Accident

Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients

Start date: April 2009
Phase: N/A
Study type: Interventional

Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya disease and stroke patients