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Motor Learning clinical trials

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NCT ID: NCT06414213 Completed - Motor Learning Clinical Trials

Improving Locomotor Learning With Brain Stimulation

ELLMITS
Start date: September 20, 2022
Phase: N/A
Study type: Interventional

The primary goal of this research was to assess the practicality and initial effectiveness of a motor imagery (MI) intervention combined with elements of action observation (AO), alongside active or sham transcranial direct current stimulation (tDCS) over the prefrontal cortex (PFC), on locomotor learning in healthy adults. Feasibility was determined by examining recruitment rates, participant engagement, and safety measures. The efficacy of the intervention was gauged by analyzing the time taken to complete tasks and changes in cerebral blood flow immediately after the intervention and one week later. The study was guided by three main hypotheses: (1) the intervention techniques would be well-received and safe for the participants; (2) compared to a control group, MI training would lead to better learning outcomes and retention of learning; (3) in comparison to the control and sham tDCS groups, active tDCS would result in superior learning outcomes and retention of learning.

NCT ID: NCT06262425 Recruiting - Clinical trials for Transcranial Magnetic Stimulation

rTMS Over S1 Enhance Motor Learning in Healthy People

Start date: January 20, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effectiveness of different repetitive Transcranial Magnetic Stimulation protocols for enhancing motor learning in healthy peolple.

NCT ID: NCT06039605 Recruiting - Expectations Clinical Trials

Priming Expectations and Motor Learning With tDCS

Start date: October 23, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to test if priming expectations of transcranial Direct Current Stimulation (tDCS) can improve the efficacy of tDCS in enhancing motor learning.

NCT ID: NCT05910814 Recruiting - Physical Exercise Clinical Trials

Effect of Physical Exercise on Motor Learning Acquired With Physical or Mental Practice

EPICA
Start date: June 16, 2023
Phase: N/A
Study type: Interventional

Motor learning is crucial for human daily routine, involving the acquisition of new movements. It consists of an online acquisition phase followed by offline consolidation, where motor memory is organized into stable representations. Acquisition can be achieved through physical practice (PP, overt repetition of movement) or mental rehearsal using motor imagery (MI). Recent studies suggest that high-intensity interval physical exercise (HIIE) enhances motor learning, particularly during consolidation, by promoting neural plasticity mediated by brain-derived neurotrophic factor (BDNF). However, the impact of HIIE on sequential motor consolidation with PP or MI remains poorly understood. In contrast, sleep deprivation (SD) reduces BDNF release and neural plasticity. Limited research has explored the effects of SD on motor acquisition, especially sequential motor learning. Considering the opposing effects of HIIE and SD, performing HIIE after SD may protect motor consolidation processes. This study aims to examine the influence of HIIE on sequential motor learning using PP or MI under both sleep-deprived and normal sleep conditions. Six groups, each comprising 12 participants, will learn an 8-item bimanual sequence. - MI group: acquired the motor sequence mentally during training - MI+HIIE group: acquired the motor sequence mentally and achieve a HIIE before the consolidation - PP: acquired the motor sequence physically - PP+HIIE group: acquired the motor sequence physically and achieve a HIIE before the consolidation - SD+PP group: one night of sleep deprivation prior physical motor acquisition with PP and consolidation - SD+PP+HIIE group: one night of sleep deprivation prior physical motor acquisition and HIIE before consolidation. All groups will be tested on the sequence at the beginning and the end of the acquisition phase (pre- and post-acquisition), and after the physical exercise (i.e. HIIE) or the rest period (post-exercise). Hypothesis of this study are : - Acute physical exercise (HIIE) would enhance the consolidation of motor memory (post-exercise) after physical and mental acquisition (PP,MI) compared to conditions without exercise. - One night of sleep deprivation would affect the acquisition and consolidation of motor learning. Physical exercise would compensate for the detrimental effects of sleep deprivation on the consolidation of motor learning.

NCT ID: NCT05467657 Recruiting - Stroke Clinical Trials

Transcranial Magnetic Stimulation on Somtosensory Cortex Enhances Motor Learning in People With Stroke

Start date: November 15, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to know the efficacy about the application of repetitive transcranial magnetic stimulation (rTMS) on the somatosensory cortex (S1) to enhance motor function in people with stroke.

NCT ID: NCT04896840 Recruiting - Cerebral Palsy Clinical Trials

Tele-rehabilitation in Children With Cerebral Palsy in the Covid-19 Pandemic

Start date: August 27, 2021
Phase: N/A
Study type: Interventional

The investigators study aimed to observe the effect of motor learning-based tele-rehabilitation on quality of life in children with cerebral palsy during the Covid-19 pandemic.

NCT ID: NCT04784832 Not yet recruiting - Motor Learning Clinical Trials

TMS-based Assessment of Mental Training Effects on Motor Learning in Healthy Participants

IMAP-TMS
Start date: December 2023
Phase: N/A
Study type: Interventional

The general purpose of this research project is to analyze the specific role of motor imagery on motor learning, assessed through corticospinal excitability measurements and behavioral data collection. This project is based on four sequences. For Sequence 1, the main objective is to examine the effect of mental training on movement speed and accuracy in a manual motor sequence task, as well as the influence of sensory feedback in immediate post-test (i.e., execution of a similar, but not identical, manual motor sequence, other manual tasks) on performance in delayed post-test. The secondary objective will be to examine corticospinal changes (i.e., amplitude of motor evoked potentials) induced by mental training, by measuring the amplitude of motor evoked potentials before and after mental training. For Sequence 2, the main objective is to examine the impact of a motor disturbance induced by a robotic arm at different intervals during the motor imagery process. The secondary objective will be to examine the corticospinal changes (i.e. amplitude of evoked motor potentials) induced by mental training as a function of the applied perturbations, before and after perturbation. For Sequence 3, the main objective will be to examine the influence of neuroplasticity on the quality of mental training. More specifically, the investigators will study the links between brain plasticity and motor learning through mental training. The secondary objective will be to examine the corticospinal changes (i.e. amplitude of evoked motor potentials) induced by mental training at different levels of the neuromuscular system (cortical, cervicomedullar, peripheral) after a training period. For Sequence 4, the main objective will be to examine the effect of short-term arm-immobilization of on the retention of motor learning induced by mental training. The secondary objective will be to examine the corticospinal changes (i.e., amplitude of motor evoked potentials) induced by of short-term arm-immobilization, or by transcranial direct current stimulation (tDCS), on motor learning. The results of this fundamental research project will allow a better understanding of neurophysiological and behavioral mechanisms that underlie motor learning through motor imagery. The results will allow to efficiently consider inter-individual specificities and will thus open up to clinical research perspectives, towards the establishment of adapted motor rehabilitation protocols.

NCT ID: NCT04690244 Completed - Healthy Aging Clinical Trials

The Effect of Tai Chi Chuan in Older Adults

Start date: June 29, 2020
Phase: N/A
Study type: Interventional

30 healthy older participants were enrolled in the study and were randomly classified into two groups. In the experimental group (n = 15) participants received 10-week Tai Chi Chuan practice intervention, in the control group (n=15) participants were asked do not change their living habits in 10 weeks. All participants had no practice Tai Chi Chuan before.

NCT ID: NCT04191083 Not yet recruiting - Motor Learning Clinical Trials

Motor Imagery and Action Observation on Motor Learning

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This study evaluates the influence of motor imagery and action observation on motor learning

NCT ID: NCT04129307 Not yet recruiting - Motor Learning Clinical Trials

Brain Training Tools With Physical Practice on Motor Learning

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This study evaluates the influence of motor imagery and action observation in combination with physical practice on motor learning