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NCT04414072 Clinical Trial

Local GIT Hormones After Bariatric Maneuvers

Morbid Obesity Clinical Trial

Official title:
Effect of Bariatric Surgery

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04414072
Other study ID # 367177
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date February 1, 2021
Est. completion date February 1, 2022

Study information
Verified date May 2020
Source Minia University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Background: Many of the beneficial metabolic effects of bariatric surgery have been attributed to altered peptide hormone profiles, especially involving pancreatic and gut peptides.

Objectives: assess the effects of bariatric procedures (sleeve gastrectomy, minigastric bypass and sleeve gastrectomy with loop bipartition) on GIT hormones. Methods: Prospective randomized study which was carried out in the department of General Surgery, Minia University hospital during the period from February 2018 to February 2019. This study included 3 groups subjected to different operations; each group consisted of 50 patients.

Description:

Prospective randomized study which was carried out in the department of General Surgery, Minia University hospital during the period from February 2018 to February 2019. This study included 3 groups subjected to different operations; each group consisted of 50 patients. Age ranging from 20 to 50 years old and body weight ranging from 100 to 200 Kg, and subjected to laparoscopic sleeve gastrectomy, mini gastric bypass and sleeve gastrectomy with loop bipartition. Each patient was thoroughly evaluated by a multidisciplinary team (Nutritionist, Endocrinologist, Psychologist, and Surgeon) using a standardized protocol. Follow up was done after two weeks and after 2 months.

Recruitment information / eligibility
Status Recruiting
Enrollment 150
Est. completion date February 1, 2022
Est. primary completion date February 1, 2021
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

All morbid obese patients

-

Exclusion Criteria:

GIT diseases

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• sleeve gastrectomy with loop bipartition
operations to decrease weight

Locations
Country Name City State
Egypt Minia university Minya

Sponsors (1)
Lead Sponsor Collaborator
Minia University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary hormonal change GIT hormones (Ghrelin, secretin, PYY, GLP-1) one year
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