Morbid Obesity Clinical Trial
Official title:
Effects of Low-Flow Anesthesia on Hemodynamic Parameters and Oxygenation in Morbidly Obese Patients Undergoing Bariatric Surgery: A Prospective, Randomized Clinical Trial
Low-flow anesthesia has been used for years with positive results, but its effects on hemodynamic parameters and oxygenation are not clearly known in high-risk morbidly obese patients who are prone to pulmonary dysfunction related to the obesity. Therefore, this prospective randomized study aimed to compare the effects of low-flow (0.75 L/min) and normal-flow (1.5 L/min) anesthesia on hemodynamic parameters and oxygenation in morbidly obese patients undergoing laparoscopic bariatric surgery.
Low-flow anesthesia has several potential benefits. It improves the flow dynamics of the
inhaled air, increase mucociliary clearance, maintain body temperature, reduce fluid loss,
result in savings of up to 75% and reduce greenhouse gas emissions and reduce treatment costs
(10 - 13). However, it is necessary to examine whether the reduction of fresh gas flow
affects the quality and safety of anesthesia management, especially during high-risk
operations such as laparoscopic bariatric surgery.
Low-flow anesthesia has been used for years with positive results, but its effects on
hemodynamic parameters and oxygenation are not clearly known in high-risk morbidly obese
patients who are prone to pulmonary dysfunction related to the obesity. Therefore, this
prospective randomized study aimed to compare the effects of low-flow (0.75 L/min) and
normal-flow (1.5 L/min) anesthesia on hemodynamic parameters and oxygenation in morbidly
obese patients undergoing laparoscopic bariatric surgery.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03657927 -
A Comparison of McGrath MAC Versus C-MAC Videolaryngoscopes in Morbidly Obese Patients
|
N/A | |
Recruiting |
NCT04934826 -
Comparison of the Absorption of Hydrolyzed or Intact Proteins in Morbid Obese Patients After the Roux Y Gastric Bypass
|
N/A | |
Completed |
NCT03181347 -
The Microbiology of Bariatric Surgery
|
N/A | |
Completed |
NCT03886870 -
Obesity, Lifestyle and Work Intervention
|
N/A | |
Active, not recruiting |
NCT04433338 -
The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery
|
N/A | |
Completed |
NCT03553849 -
Utilization of Very Low Calorie Diet in Obese General Surgery Patients
|
N/A | |
Completed |
NCT05854875 -
Diabetes Remission After RYGBP and RYGBP With Fundus Resection
|
N/A | |
Not yet recruiting |
NCT03203161 -
Registry on Obesity Surgery in Adolescents
|
||
Not yet recruiting |
NCT03601273 -
Bariatric Embolization Trial for the Obese Nonsurgical
|
Phase 1 | |
Recruiting |
NCT02129296 -
Intragastric Balloon, Air Versus Fluid Filled: Randomized Prospective Study
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT01564732 -
Multicenter Prospective Randomized Controlled Trial of Plicated Laparoscopic Adjustable Gastric Banding
|
N/A | |
Completed |
NCT02033265 -
Ultrasound-Guided Axillary Brachial Plexus Block: Influence of Obesity
|
||
Completed |
NCT01963637 -
Gastric Volumetry by Gastric Tomodensitometry With Gas
|
N/A | |
Not yet recruiting |
NCT01652105 -
Randomized Trial of Preoperative Diets Before Bariatric Surgery
|
N/A | |
Completed |
NCT01955993 -
Fentanyl Metabolism in Obese Adolescents
|
N/A | |
Terminated |
NCT01759550 -
Prospective Case-Series of Ligasure Advance Pistol Grip and LigaSure Blunt Tip
|
||
Completed |
NCT01149512 -
Outcomes of the Adjustable Gastric Band in a Publicly Funded Obesity Program
|
N/A | |
Recruiting |
NCT01685177 -
Single Anastomosis Duodeno-Ileal Bypass vs Standard Duodenal Switch as a Second Step After Sleeve Gastrectomy in the Super-Morbid Obese Patient
|
N/A | |
Completed |
NCT02414893 -
Hunger/Satiety's Physiopathologic Study in Morbidly Obese Patients
|
N/A | |
Completed |
NCT01536197 -
Taste Perception Pre and Post Bariatric Surgery
|
N/A |