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Morbid Obesity clinical trials

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NCT ID: NCT01254266 Recruiting - Morbid Obesity Clinical Trials

The Efficacy of an Inpatient Program for Long-term Weight Maintenance in Children and Adolescents With Morbid Obesity

Start date: December 2010
Phase: N/A
Study type: Interventional

The major problem in the treatment of morbidly obese children is the long term maintenance of the reduced weight. Maintenance-focused interventions have not been studied enough in adolescents with morbid obesity, neither in regard to conservative methods of weight reduction, nor in regard to bariatric surgeries. This study will investigate the effectiveness of an integrative, multi-disciplinary inpatient program for promoting long-term weight maintenance in children with morbid obesity. The program will be studied in two perspectives: as a conservative treatment, as well as an 'envelope' for bariatric surgeries including a pre-operational preparation phase and a post-operational follow-up. The investigators hypothesize that program participants will maintain weight significantly better than the proportion known in the literature.

NCT ID: NCT01078194 Recruiting - Morbid Obesity Clinical Trials

Secondary Bypass Banding for Weight Regain or Weight Loss Failure After Lap. Gastric Bypass

Start date: January 2010
Phase: N/A
Study type: Observational

This is an observational study on the efficacy of the secondary placement of the A.M.I Soft Gastric Band in weight regain or weight loss failure after lap. gastric bypass.

NCT ID: NCT01078181 Recruiting - Morbid Obesity Clinical Trials

Banded Versus Non-banded Roux-en-Y Gastric Bypass

Start date: November 2009
Phase: N/A
Study type: Interventional

This is a prospective randomized Study comparing Weight loss, Esophageal Motility and Reflux in lap. Gastric Bypass vs. lap. Banded-Gastric Bypass using the A.M.I. Soft Gastric Bypass Band (B-Band.

NCT ID: NCT01002599 Recruiting - Morbid Obesity Clinical Trials

Oxygenation and Pulmonary Function in Morbidly Obese Patients Undergoing Bariatric Surgery

Start date: June 2009
Phase: N/A
Study type: Interventional

This is a randomized controlled study in which morbidly obese patients undergoing bariatric surgery will be recruited in the preoperative clinic. Patients will be randomized into 2 groups to receive oxygen with Boussignac TM continuous positive airway pressure (CPAP) or conventional Venturi mask postoperatively immediately after extubation. The objective of the study is to examine if Boussignac TM CPAP results in improved oxygenation versus Venturi face mask when it is applied immediately after extubation in morbidly obese patients post bariatric surgery.

NCT ID: NCT00914446 Recruiting - Morbid Obesity Clinical Trials

Identification of Protective and Worsening Steatohepatitis (NASH) Factors

Start date: April 2008
Phase: N/A
Study type: Interventional

The main aim of this work will be to identify a profile of gene expression by microarray in the liver which might allow to differentiate obese subjects having a normal liver from those with steatohepatitis or steatosis.

NCT ID: NCT00875186 Recruiting - Morbid Obesity Clinical Trials

The Influence of Aerobic Endurance Training After Roux-en-Y-Gastric Bypass

AET
Start date: October 2006
Phase: N/A
Study type: Observational

The aim of this study was to assess the efficiency of aerobic physical exercise (APE) on weight loss, body composition and co-morbidities in patients after laparoscopic Roux-en-Y Gastric bypass (RYGBP).

NCT ID: NCT00872378 Recruiting - Morbid Obesity Clinical Trials

The Effects of Exenatide After Gastric Restriction

AGREE
Start date: February 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to describe change in body weight in non-diabetic morbidly obese patients after laparoscopic adjustable gastric banding (LAGB) with twice daily exenatide or placebo injections.

NCT ID: NCT00502021 Recruiting - Atherosclerosis Clinical Trials

Use of Flaxseed(Alpha Linolenic Acid) Powder in Morbidly Obese Patients With Systemic Inflammation

Start date: August 2007
Phase: Phase 2
Study type: Interventional

Preliminary studies have shown that flaxseed powder, rich in the omega-3 alpha-linolenic acid,is beneficial for the general inflammation present in morbidly obese subjects by decreasing elevated serum markers.As omega-3 fatty acids display additional properties including possible amelioration of atherosclerosis,a 3-month supplementation protocol was devised.Arterial stiffness and intima thickness will be measured in severely obese subjects, in order to document possible reduction of these variables as well.

NCT ID: NCT00431587 Recruiting - Metabolic Syndrome Clinical Trials

Changes in Different Fat Compartments and Their Effect on Particular Manifestations of Metabolic Syndrome After Bariatric Procedures.

Start date: June 2007
Phase: N/A
Study type: Observational

The metabolic risks associated with obesity are closely correlated with central (abdominal), rather than a peripheral (gluteofemoral) fat pattern It has been shown that weight loss after bariatric surgery is followed by metabolic improvements. The amount of fat lost from each site may be independently regulated. Very scant information is found in the literature regarding the relative changes in different fat body compartments, and their effect on the improvement of the metabolic profile. In this study we define the absolute and relative changes in the different adipose tissue compartment after weight loss surgery

NCT ID: NCT00351338 Recruiting - Morbid Obesity Clinical Trials

Nutritional Deficiencies in the Bariatric Patients

Start date: July 2006
Phase: N/A
Study type: Observational

Although morbidly obese subjects have larger than regular caloric intake, there is evidence that they suffer from nutritional deficiencies at a higher rate than the general population, probably because they eat mostly "unhealthy food."