Effect of Coffeeberry on Mood, Motivation and Cognitive Performance

Mood Clinical Trial

Official title:

Effect of Coffeeberry on Mood, Motivation and Cognitive Performance

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04974606
• Other study ID #: PEP-1605
• Status: Completed
• Phase: N/A
• Start date: June 28, 2016
• Est. completion date: December 16, 2016

Study information

• Verified date: July 2021
• Source: PepsiCo Global R&D
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The primary purpose is to test the short-term effects of the acute consumption of two novel beverages made from coffeeberries, the fruit of the coffee plant (Coffea arabica) benchmarked against caffeine on several aspects of cognitive performance.

Preliminary studies suggest that flavanols and chlorogenic acids can enhance cognitive performance. It is unknown if drinks formulated with flavanols and chlorogenic acids (without high sugar or caffeine) improve cognition or mood to a similar extent as caffeine. Coffeeberry beverage comparisons will be made to a flavored positive control beverage containing caffeine and a flavored placebo beverage.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: December 16, 2016
• Est. primary completion date: December 16, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 17 Years to 50 Years

Eligibility

Inclusion Criteria:

• Are older than 17 and under 50 years of age

• Self-report of good health

Exclusion Criteria:

• Using any prescription medication including birth control

• Report hypersensitivity to caffeine

• Have visual impairment that cannot be corrected with glasses or contact lenses

• Report any food allergies

• Self-reported excessive leisure time physical activity (> 7 strenuous bouts per week)

• the presence of current gastrointestinal, sleep, or psychiatric disorder,

• Report pregnancy/lactation, illegal drug use, smoker

• failure to demonstrate adequate minimal performance on lab, computer-based cognitive tasks.

• Participation in another clinical trial within past 30 days

Related Conditions & MeSH terms

• Alertness
• Cognitive Performance
• Fatigue
• Fatigue, Mental
• Mental Fatigue
• Mood
• Motivation

Intervention

Dietary Supplement:
• Cherry-flavored still beverage
10 oz bottle

Other:
• Placebo cherry-flavored still beverage
10 oz bottle

Locations

Country	Name	City	State
United States	Exercise Psychology Laboratory University of Georgia	Athens	Georgia

Sponsors (1)

Lead Sponsor	Collaborator
PepsiCo Global R&D

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cognition score	Objective Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS) for word and picture presentation and recall, serial 3 and 7 subtraction, Rapid Visual Information Processing (RVIP).	Change from baseline to 60 and 120 min post-consumption. Higher test scores are better.
Primary	Fatigue score	Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS)	Change from baseline to 60 and 120 min post-consumption. Lower fatigue score is better.
Primary	Alertness score	Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)	Change from baseline to 60 and 120 min post-consumption. Higher alertness score is better.
Primary	Calmness score	Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)	Change from baseline to 60 and 120 min post-consumption. Higher calmness score is better.
Primary	Contentedness score	Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)	Change from baseline to 60 and 120 min post-consumption. Higher contentedness score is better.
Primary	Motivation score	Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)	Change from baseline to 60 and 120 min post-consumption. Higher motivation score is better.
Primary	Energy score	Subjective mental and physical state energy and fatigues scales (EFS-State Scale). Composite scores range from 0 to 300 mm, from feelings of no energy to strongest feelings of energy during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS)	Change from baseline to 60 and 120 min post-consumption. Stronger feelings of mental and physical energy are better.