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Mental Fatigue clinical trials

View clinical trials related to Mental Fatigue.

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NCT ID: NCT05679882 Recruiting - Clinical trials for Heart Rate Variability

Effects of Natural Sounds on Attention Restoration Outdoors

NEO
Start date: October 24, 2022
Phase: N/A
Study type: Interventional

This study aims to examine whether listening to natural sounds in a noisy outdoor environment compared to no natural sounds influences behavioural, cognitive, affective, and physiological markers.

NCT ID: NCT05679869 Recruiting - Clinical trials for Heart Rate Variability

Effects of Natural Sounds on Attention Restoration in Virtual Reality

VEARS
Start date: December 6, 2022
Phase: N/A
Study type: Interventional

This study aims to examine whether listening to natural sounds in a noisy virtual reality environment compared to no natural sounds influences physiological markers.

NCT ID: NCT05678374 Recruiting - Autoimmune Diseases Clinical Trials

Exploring Immunological Markers Associated With Mental Fatigue in Graves' Disease

Start date: October 1, 2019
Phase:
Study type: Observational

Mental fatigue occurs in many diseases and the reasons are mostly unknown. The investigators hypothesize that remaining mental fatigue after restored hyperthyroidism in Graves' disease is an autoimmune complication. The aim of this study is to explore immunological markers possibly associated with mental fatigue in Graves' disease, which the investigators plan to validate in another study (ImmunoGraves wp 2). Using a cross-sectional study design, mental fatigue is scored using a questionnaire to find 60 patients with and 60 without mental fatigue 15-60 months after diagnosis of Graves disease. The patients and 60 thyroid healthy controls without mental fatigue are assessed for thyroid hormones, quality of life, anxiety and depression, self-evaluated stress, coping strategies, eye symptoms and background variables. SciLifeLab in Stockholm, the national facility for autoimmune profiling, has pre-set large arrays including 42000 human proteins. Serum and cerebrospinal fluid will be separately pooled and analysed for a subgroup of patients with or without mental fatigue and for a subgroup of the control group. Proteins that preferably bind to antibodies in sera and/or cerebrospinal fluid from Graves' patients with mental fatigue in comparison to non-mental fatigue patients, will be screened against the Human Protein Atlas and the Allen brain map to identify those proteins that are expressed in the brain. Antibodies at higher concentration in the mental fatigue pools compared to the group without mental fatigue will be selected for further analyses on an individual level in the whole cohort together with antibodies targeting g-protein coupled receptors, thyroid autoantibodies, cytokines and biomarkers indicating organic and structural nerve damage.

NCT ID: NCT05576935 Recruiting - Mental Fatigue Clinical Trials

The Individual Response of Healthy Individuals to Mental Fatigue

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

The objective of the present study is to confirm and map out the presence of interindividual differences in the effect of mental fatigue on both physical and cognitive performance, and to see if these differences are related to individual factors of the participants.

NCT ID: NCT05559034 Completed - Mental Fatigue Clinical Trials

Brain Oxygenation Marker for Cognitive Function in Healthy Adults

Twilight
Start date: September 6, 2022
Phase:
Study type: Observational [Patient Registry]

This study aims to identify a cortical oxygenation marker for cognitive function using functional Near Infrared Spectroscopy in healthy adults.

NCT ID: NCT05530915 Completed - Clinical trials for Attention Difficulties

Guayusa: The Effect of an Herbal Extract on Alertness and Mental Fatigue

Start date: July 27, 2022
Phase: N/A
Study type: Interventional

The primary objective of this randomized, double-blind, placebo-controlled, cross-over study is to assess the acute effects of a novel ingredient, guayusa on alertness and mental fatigue compared to a placebo. This trial will utilize the COMPASS cognitive task and cognitive demand battery (CDB) and mood, motivation, and energy measures with assessments taking place at baseline, 60- and 120-minutes post treatment on three separate testing days separated by ~7 days.

NCT ID: NCT05528094 Active, not recruiting - Mental Fatigue Clinical Trials

An Exploratory Investigation of a Supplement to Support Student Learning

Start date: April 14, 2022
Phase: N/A
Study type: Interventional

In this trial, the herbal supplement (GeniusDrops) will be tested to see the effects it has on the dependent variables of interest. Participants will take the supplement twice a day for a month and respond to surveys at study baseline, midpoint, and the conclusion of the study. The findings of this study will be used for marketing materials and to inform future trials using the supplement.

NCT ID: NCT05524233 Not yet recruiting - Brain Fog Clinical Trials

Transcranial Direct Current Stimulation (tDCS)

tDCS
Start date: September 15, 2022
Phase: N/A
Study type: Interventional

Cognitive impairment refers to when an individual struggles to learn, concentrate, remember, or make decisions. This can be due to underlying neurological diseases (i.e. Alzheimer's disease, dementia, etc.), caused by viral illness (i.e. brain fog experienced by COVID-19 survivors) or physical trauma (i.e. concussion). Recent reports indicate that two out of three Americans experience some amount of cognitive impairment in their lifetime. There are a number of therapies that have been used to help address this condition. One of these is transcranial direct current stimulation (tDCS), which delivers sustained direct current to to the head area via electrodes. A number of studies have indicated that this form of therapy is safe and efficacious at inducing neuroplasticity and exciting neuronal activity. These factors can help improve aspects of cognitive functioning such as working memory, learning, and task performance. The purpose of this pilot study is to examine the acceptability and proof of concept effectiveness of a wireless, transcranial direct current stimulation for people with cognitive impairments.

NCT ID: NCT05519774 Recruiting - Brain Fog Clinical Trials

Assessment of Cancer Related Brain Fog Using the Test of Strategic Learning

ACT I
Start date: August 1, 2022
Phase:
Study type: Observational

The Inova research team will ask people who have had an experience of breast cancer and related changes to their cognition to complete some scales that researchers have established describe brain fog (called patient reported outcomes) and compare those results to the TOSL results. This will be done twice to see if changes are detected similarly on both types of measures.

NCT ID: NCT05466136 Recruiting - Mental Fatigue Clinical Trials

Mindfulness, Mental Fatigue, Inhibitory Control and Endurance Performance in Athletes

Start date: April 20, 2022
Phase: N/A
Study type: Interventional

This study investigated the mediating effect of dispositional mindfulness on the impact of mental fatigue on neurocognitive functions and endurance performance in athletes.