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Mitral Valve Insufficiency clinical trials

View clinical trials related to Mitral Valve Insufficiency.

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NCT ID: NCT00554151 Completed - Clinical trials for Mitral Valve Regurgitation

Mitral Adjustable Annuloplasty Ring Feasibility and Safety Study

MAARS
Start date: July 2007
Phase: N/A
Study type: Interventional

Evaluation of the technical feasibility and safety of the Mitral Adjustable Annuloplasty Ring.

NCT ID: NCT00512005 Recruiting - Heart Failure Clinical Trials

VIVID - Valvular and Ventricular Improvement Via iCoapsys Delivery - Feasibility Study

VIVID
Start date: January 2008
Phase: Phase 1
Study type: Interventional

The purpose of this prospective, non-randomized, single-arm feasibility study is to evaluate safety and feasibility of the iCoapsys System in patients with functional mitral valve insufficiency caused by annular dilation and/or papillary muscle displacement.

NCT ID: NCT00509080 Active, not recruiting - Clinical trials for Mitral Regurgitation

Prognosis in Asymptomatic Mitral Regurgitation (PAMIR) Study

Start date: April 2006
Phase:
Study type: Observational

The purpose of this study is to determine if the use of BNP/NT-proBNP levels in the detection of early left ventricular dysfunction and damage may improve the timing of cardiac surgery and therefore the long-term management of asymptomatic patients with severe mitral regurgitation.

NCT ID: NCT00491452 Completed - Clinical trials for Mitral Regurgitation

Repair of Ischemic Mitral Regurgitation: Comparison Between Flexible and Rigid Annuloplasty Rings

IMR2
Start date: April 2007
Phase: N/A
Study type: Observational

Mitral valve repair for ischemic mitral regurgitation is performed primarily by annuloplasty. There is some degree of late failure, which may be due in part to the type of ring employed. We want to compare late results with mitral valve annuloplasty using flexible vs rigid annuloplasty rings.

NCT ID: NCT00483236 Withdrawn - Clinical trials for Congestive Heart Failure

Prospective Study Looking at Quality of Life Measures in Non-ischaemic Cardiomyopathy After Mitral Valve Repair

Start date: December 1, 2007
Phase:
Study type: Observational

- Chronic severe mitral regurgitation can lead to symptoms and left ventricular dysfunction. - The purpose of this study is to prospectively follow patients with non-ischaemic cardiomyopathy who are eligible for mitral valve repair surgery and primarily measure the quality of life through the Minnesota Living with Heart Failure Questionnaire & the Kansas City Cardiomyopathy Questionnaire.

NCT ID: NCT00443365 Recruiting - Coronary Disease Clinical Trials

Should we Repair Ischemic Mitral Regurgitation?

Start date: March 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether adding mitral valve repair to coronary artery bypass grafting improves outcome in patients with ischemic mitral regurgitation.

NCT ID: NCT00428103 Withdrawn - Clinical trials for Congestive Heart Failure

Effects of Mitral Valve Repair With the Geoform Ring on Cardiomyopathy

Start date: October 2006
Phase: N/A
Study type: Interventional

The primary aim of this study is to assess the changes on the shape and function of the left ventricle in patients with severe mitral valve regurgitation due to congestive heart failure and cardiomyopathy who undergo mitral valve reconstruction with a Geoform ring. Three-dimensional echocardiogram will be used for precise evaluation of the shape and function of the ventricle.

NCT ID: NCT00415701 Completed - Clinical trials for Coronary Artery Disease

Effect of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery

Start date: November 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effect of a single dose of etomidate for patients undergoing cardiac surgery with the use of cardiopulmonary bypass (CPB) on post-CPB adrenocortical responsiveness, on requirements of hemodynamic support, and on use of intensive care resources.

NCT ID: NCT00413998 Completed - Clinical trials for Coronary Artery Disease

Randomised Ischaemic Mitral Evaluation (RIME) Trial

RIME
Start date: January 2007
Phase: Early Phase 1
Study type: Interventional

The study is a randomised controlled trial comparing two treatment strategies for patients with moderate functional ischaemic mitral regurgitation undergoing coronary artery bypass grafting (CABG). Patients will be randomised to receive either CABG alone or CABG plus mitral annuloplasty. The objective of the study is to determine if mitral annuloplasty in addition to CABG improves outcome in patients with moderate functional ischaemic mitral regurgitation.

NCT ID: NCT00394797 Completed - Clinical trials for Moderate Ischemic Mitral Regurgitation

Surgical Correction of Moderate Ischemic Mitral Regurgitation

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this study is to try and determine whether repair of moderate ischemic mitral regurgitation at the time of coronary bypass graft surgery (CABG) has an impact on survival.We will compare patients undergoing CABG + mitral repair or CABG only groups. Primary endpoints include late survival. Secondary endpoints include event free survival, symptoms, and echocardiographic outcomes.