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Clinical Trial Summary

The main purpose of this study is to investigate the safety of the investigational drug DCC-2701 and whether it will work to help people who have advanced solid tumors or cancer that has spread to other parts of the body.


Clinical Trial Description

This is a first-in-human study of DCC-2701. The primary purpose of this study is to determine what dose of DCC-2701, can be given safely to patients with advanced solid tumors.

The study will have two phases. The first phase will assess escalating doses of DCC-2701 in order to determine the maximally tolerated dose (MTD) and the optimal dosing regimen (ODR) of DCC-2701. Once the MTD and ODR is established, a dose expansion phase will further evaluate the safety of DCC-2701, as well as the activity of DCC-2701 in select solid tumor types. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02228811
Study type Interventional
Source Deciphera Pharmaceuticals LLC
Contact
Status Terminated
Phase Phase 1
Start date June 2014
Completion date January 2018

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