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Gut Microbiome and Obesity — MATOMS  

Metabolic Syndrome Clinical Trial

Official title:
Gut Microbiome As Target of Intervention Against Obesity and Metabolic Syndrome

Clinical Trial Summary

Pediatric obesity is a risk factor for the onset of obesity in adulthood and is a risk factor for various chronic non-communicable diseases. Metabolic syndrome (MS) is the name for a group of risk factors that increase cardiovascular risk and other health problems characterized by the presence of abdominal obesity, dyslipidemia, hyperglycaemia and high blood pressure. Numerous preclinical and clinical data suggest a potential role of the intestinal microbiota in these diseaes. Unfortunately, comparative studies of the gut microbiota are still scarce in pediatric subjects suffering from obesity than obesity complicated by MS. The aim is to study the metagenomics and metabolomics characteristics of the intestinal microbiota in obese children/adolescents with or without MS, that could provide useful data for innovative intervention strategies for these conditions.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04451148
Study type Observational
Source Federico II University
Contact
Status Recruiting
Phase
Start date May 1, 2020
Completion date May 1, 2022
View Details
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