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Mental Fatigue clinical trials

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NCT ID: NCT05100667 Recruiting - Hypoxia Clinical Trials

A Potential Role for Oxygen in the Development of Mental Fatigue and the Subsequent Decline in Cognitive Performance

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Introduction Both Mental Fatigue (MF) and hypoxia impair multiple aspects of cognitive functioning. The decline in cognitive functioning in hypoxic conditions is associated with alterations in brain oxygenation and hemodynamic responses. These hemodynamic responses are preferably measured at the prefrontal cortex, an area of the brain that is known for its executive function and role in decision making, planning, attention and (short-term) memory. This study will investigate the role of prefrontal cortex oxygenation during the development of mental fatigue and during cognitive performances by altering the ambient oxygen availability through normobaric hypoxia (3800m; 12,9% O2) and normoxia. Methods Subjects will perform four trials in a sound-insulated climate chamber (20°C and 40% RH). Upon entry in the climatic chamber participants will adapt to the environment for 30 minutes. Next, they will perform a modified cognitive test battery "cognition", a fine motor task "Motor Performance Series" and a visuomotor-fitlight task before and after a 60-minute individualized Stroop task or control task (randomized. blinded, placebo controlled, counter-balanced, cross-over design). Nearinfrared spectroscopy (NIRS) will be used to assess hemodynamic changes (oxygenated hemoglobin (O2Hb), deoxygenated-hemoglobin (HHb) and total hemoglobin (tHb)) at the PFC. Hypotheses 1) MF will lead to earlier changes in the prefrontal NIRS-parameters (O2Hb, HHb, tHb) with lower oxygen availability. 2) The effects of MF on cognitive performance manifest itself to a greater extent with lower oxygen availability.3) Visuomotor performance declines to a greater extent due to MF with lower oxygen availability.

NCT ID: NCT05012293 Recruiting - Clinical trials for Heart Rate Variability

Cognitive Fatigue, Self-Regulation, and Academic Performance: A Physiological Study

FRAPS
Start date: August 26, 2021
Phase: N/A
Study type: Interventional

This study aims to examine the relationship among cognitive fatigue, self-regulation, and academic performance.

NCT ID: NCT05011318 Recruiting - Clinical trials for Heart Rate Variability

Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance

FRESH
Start date: August 25, 2021
Phase: N/A
Study type: Interventional

This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.

NCT ID: NCT05009784 Recruiting - Clinical trials for Heart Rate Variability

Effects of Natural Sounds on Attention Restoration in Noisy Environment

EARS
Start date: August 25, 2021
Phase: N/A
Study type: Interventional

This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention restoration. Attention restoration will be examined as an aspect of cognitive fatigue.

NCT ID: NCT03580304 Recruiting - Mental Fatigue Clinical Trials

Evaluation of Physical and Cognitive Industrial Workload

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The main aim of the project is to evaluate a novel upper body exoskeleton during simulated industrial work. In this stage of the project, a study analysing the physical and mental load during occupational work will be carried out. High risk tasks will be identified in the field and simulated in lab-setting to analyse physical and mental load using physiological and biomechanical data.These will include, but will not be limited to, non-ergonomic postures, for example performing operations above the head or reaching in front of, to the side of, or behind the body; flexing the arms for extended periods of time; and bending or twisting the torso to lift an object from low or distant locations. Important items to assess in this task are the frequency and duration of tasks and activities, lifting characteristics, perceived physical effort and work-induced fatigue.

NCT ID: NCT02867657 Recruiting - Inflammation Clinical Trials

Bringing the Practice of Mindfulness Into Nature - Preventing Mental Fatigue in Healthcare Professionals.

Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether a five day mindfulness retreat in nature can increase measures of attention and self-compassion, and reduce stress among bachelor students at Danish Universities and University Colleges. Secondary whether the expression of inflammatory markers can be reduced . It is the hypothesis that perceived stress is reduced and the expression of genetic markers of inflammation is reduced after a five day mindfulness retreat.