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Medication Adherence clinical trials

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NCT ID: NCT06175559 Active, not recruiting - Clinical trials for Medication Adherence

Embedded Narrative in Interactive Game Design for Improving Medication Adherence of Schizophrenia

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

This study explores the potential of an interactive narrative game to enhance medication adherence among stable schizophrenia patients. Employing participatory design methods, game's development and testing process actively involved patients and individuals closely connected to their daily lives. Artificial Intelligence-Generated Content (AIGC) facilitated swift iterations in game's visual style and content. During game therapy, patients are tasked with making decisions based on presented situations, which influence the course of the narrative.

NCT ID: NCT05349422 Active, not recruiting - Blood Pressure Clinical Trials

Addressing Antihypertensive Medication Adherence Through EHR-enabled Teamlets in Primary Care

Start date: October 6, 2022
Phase: N/A
Study type: Interventional

The study team will conduct a cluster randomized control trial in 10 NYU primary care practices to assess the effectiveness and implementation of the multicomponent intervention on medication adherence and blood pressure control for patients who are non-adherent to antihypertensive medications.

NCT ID: NCT05150028 Active, not recruiting - Clinical trials for Medication Adherence

A Virtual Intervention to Improve Medication Adherence in Pediatric Cancer: MedSupport

Start date: April 11, 2023
Phase: N/A
Study type: Interventional

To develop a cancer center level practice intervention to promote treatment adherence and reduce outcome disparities in pediatric cancer survivors

NCT ID: NCT05098743 Active, not recruiting - Clinical trials for Medication Adherence

The Influence of a Medication Adherence Smartphone Application on Medication Adherence in Chronic Illness

Start date: November 19, 2021
Phase: N/A
Study type: Interventional

Medication adherence is a critical aspect of achieving optimal health outcomes. Thirty to 50% of patients adhere to long-term medication treatment of chronic diseases. Non adherence has been shown to result in worsening disease, increased healthcare expenditures, complications and even death. Medically underserved communities have higher rates of medication nonadherence and a higher prevalence of chronic conditions and often receive care at Federally Qualified Health Centers (FQHCs) which are reporting caring for increasingly complex chronic conditions. Smartphone mobile phone ownership has increased to 76% in low income Americans, but this population has been underrepresented in mobile health intervention studies. This two-group, cluster randomized by site, randomized controlled trial will investigate the effect of a medication adherence smartphone mobile application (app) which provides reminders on patient medication adherence, on medication self-efficacy, medication knowledge and medication social support. Independently, each of these concepts have been shown to support medication adherence. However in the context of delivery by a medication adherence app in a variety of chronic illnesses in a medically underserved population, little is known. It will also explore if those who accessed educational materials within the app report greater medication knowledge than those who do not and if participants who choose to use the additional Medfriend feature report greater medication social support than those who do not. The study will also explore patients' perceptions on the usefulness and satisfaction with the app features.

NCT ID: NCT05051124 Active, not recruiting - Hypertension Clinical Trials

Peers and Technology for Adherence, Access, Accountability, and Analytics

PT4A
Start date: April 19, 2022
Phase: N/A
Study type: Interventional

The overall objective of this project is to utilize the PRECEDE-PROCEED framework to conduct transdisciplinary, translational implementation research focused on improving medication adherence for hypertension control. The central hypothesis is that peer delivery of medications integrated with HIT (PT4A) will be effective in improving hypertension medication adherence, contributing to improved blood pressure among patients with uncontrolled hypertension in western Kenya. This study record will focus on Sub-Aim 2.2: a pilot of the intervention and a survey questionnaire with patients, peers, and clinical staff to evaluate feasibility. The investigators will evaluate impact on systolic blood pressure, medication adherence, and fidelity of implementation. The investigators will also create a retrospective comparator (control) group of CDM patients, through querying AMRS, matched by sex, age, location and initial blood pressure level. The investigators will then use their recorded blood pressure over a comparable period of up to 1 year and to allow for comparison to the blood pressure changes observed in the patients enrolled in the PT4A program to help understand the magnitude and variance of the intervention effects.

NCT ID: NCT04347161 Active, not recruiting - Lung Cancer Clinical Trials

Implementation Strategies for Monitoring Adherence in Real Time

iSMART
Start date: February 22, 2021
Phase: N/A
Study type: Interventional

The objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies. To achieve this objective, we will evaluate the effect of a novel, bidirectional conversational agent, compared to usual care, on adherence to oral targeted therapies using a two-arm randomized controlled trial, and explore how multilevel factors impact the acceptability and effectiveness of this strategy by collecting qualitative and quantitative data from clinicians and patients.

NCT ID: NCT04078750 Active, not recruiting - Clinical trials for Medication Adherence

PLATO - Medication Adherence in Transplant Recipients

Start date: September 10, 2019
Phase: N/A
Study type: Interventional

Non-adherence with immunosuppressant drugs is a major reason for premature kidney transplant failure. Currently, patient education and compliance aids (e.g bubble packing) are commonly used to assist patients. This is a study involving patients expected to undergo a kidney transplant within 6 months. One group will undergo a one-month formal assessment of adherence before transplantation using mock immunosuppressant medication. Standardized surveys will also be administered to assess risk factors for non-adherence. A plan will be developed for use after the transplant. The other group will undergo usual care. Kidney function and rejection rates will be compared between two groups.

NCT ID: NCT04029883 Active, not recruiting - Hypertension Clinical Trials

Behavioral Economics to Improve Antihypertensive Therapy Adherence

BETA
Start date: April 19, 2022
Phase: N/A
Study type: Interventional

Hypertension represents a major cardiovascular risk factor that can be controlled through the use of medications, yet medication non-adherence represents a common problem that leaves patients at elevated risk for adverse cardiovascular outcomes. Interventions to improve medication adherence have thus far been either unsuccessful or unsustainable. The investigators propose an intervention that leverages insights from behavioral economics to improve medication adherence among hypertensive patients. Strong data indicates that linking the taking of medications to daily routines ('anchoring') increases adherence, however, existing interventions built on this information have failed to create successful, long term improvements in medication adherence. This study aims to leverage behavioral economic insights to improve medication adherence to antihypertensive medications.

NCT ID: NCT03973931 Active, not recruiting - Hypertension Clinical Trials

Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

The study plans to learn if sending different text messages, serving as reminders or encouragement, may help patients take their medication more often if they have had trouble keeping up with their medicines.

NCT ID: NCT03885674 Active, not recruiting - Stroke Clinical Trials

Improving Medication Self-Administration and Health After Brain Injury

Start date: July 2016
Phase: N/A
Study type: Interventional

The purpose of this research study is to assess medication self-administration (MSA) and the impact of three different interventions on improving medication adherence. The findings for this study may help develop evidence-based reminder protocols to reduce medication self-administration errors after brain injury.