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Clinical Trial Summary

The aim of the study was to establish a clinical and advanced imaging database of acute ischemic stroke patients treated with mechanical thrombectomy due to large vessel occlusion of anterior circulation within 24 hours from stroke onset in China, and to investigate the predictors and potential mechanisms of futile recanalization after mechanical thrombectomy.


Clinical Trial Description

The time-window of mechanical thrombectomy for ischemic stroke has extended from 4.5 hours to 24 hours based on the results of the DAWN and DEFUSE 3 trials. However, evidence on the effectiveness and safety of mechanical thrombectomy within 24 hours in the real-world is insufficient. This is a multi-center, prospective, registry cohort study that acute ischemic stroke patients treated with mechanical thrombectomy due to large vessel occlusion of anterior circulation within 24 hours from stroke onset in China. A retrospective dataset was also build in these stroke centers for analysis. A total of 1600 patients with advanced imaging data were anticipated to be enrolled. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05311605
Study type Observational [Patient Registry]
Source Beijing Tiantan Hospital
Contact Yunyun Xiong, MD, PhD
Phone 00861059975213
Email xiongyunyun@bjtth.org
Status Recruiting
Phase
Start date February 23, 2023
Completion date December 31, 2024

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