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Mechanical Thrombectomy clinical trials

View clinical trials related to Mechanical Thrombectomy.

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NCT ID: NCT04870684 Not yet recruiting - Clinical trials for Cerebrovascular Stroke

Thromboelastometry and Ischemic Stroke (ThromboPredict)

Start date: May 1, 2021
Phase:
Study type: Observational

In ischemic stroke, the recanalization rate after intravenous thrombolysis has been estimated to be less than 50% in patients with proximal intracranial artery occlusion; this rate is greater than 80% after endovascular thrombectomy. Thromboelastometry is a method of analysis of coagulation and fibrinolysis in whole blood. The main objective of this study is to evaluate whether the parameters obtained by thromboelastometry are predictive of revascularization at arteriography during mechanical thrombectomy, after treatment with rt-PA thrombolysis.

NCT ID: NCT04664933 Recruiting - Stroke, Ischemic Clinical Trials

Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET)

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who received recanalization operation.

NCT ID: NCT04484350 Completed - Blood Pressure Clinical Trials

Blood Pressure Management in Stroke Following Endovascular Treatment

DETECT
Start date: October 23, 2020
Phase: Phase 2
Study type: Interventional

The aim of DETECT is to prove the feasibility of a multicenter phase III trial testing the hypothesis that intensive blood pressure control immediately after successful endovascular stroke thrombectomy can improve patient outcomes. Patients with stroke who have ongoing high blood pressure after successful clot retrieval will be included. Participants will be randomly placed (like flipping a coin) in one of two groups. There will be a 50% chance of each patient being placed to either group. The first group will be allowed to have a higher blood pressure range that is consistent with current recommendations. The second group will be given medications to bring their blood pressure down into a normal range. These blood pressure targets will be maintained for 48 hours. We will collect patient brain images and levels of stroke disability up to 90 days after their clot retrieval.

NCT ID: NCT03754738 Recruiting - Stroke Clinical Trials

Efficacy and Safety of Balloon Guide Catheter in Mechanical Thrombectomy Patients

ESCAPE
Start date: November 25, 2018
Phase: Phase 2
Study type: Interventional

With mechanical thrombectomy now representing standard of care for treatment of acute ischemic stroke secondary to large vessel occlusion, identifying adjunctive techniques that result in improved outcomes for patients with LVO has become an issue of increasing importance. A number of retrospective studies have demonstrated that flow arrest during the clot retrieval process results in less clot fragmentation, lower rates of distal emboli, higher revascularization rates and improved rates of good neurological outcome.

NCT ID: NCT03702413 Completed - Clinical trials for Mechanical Thrombectomy

Randomized Controlled Trial of Endovascular Therapy for Acute Large Vessel Occlusion With Large Ischemic Core

Start date: November 30, 2018
Phase: N/A
Study type: Interventional

RESCUE-Japan LIMIT(Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism Japan Large IscheMIc core Trial) is a prospective, open label, blinded endpoint (PROBE), Japanese, two-arm, randomized, controlled, post-market study to compare the effectiveness of endovascular treatment as compared to best medical treatment alone in the acute ischemic stroke patients with an low ASPECTS (CT-ASPECTS 3-5 or DWI-ASPECTS 3-5). The purpose of this study is to investigate the efficacy of endovascular treatment for acute large vessel occlusion with large ischemic core (CT-ASPECT score 3-5 or DWI-ASPECT score 3-5).