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Mass Screening clinical trials

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NCT ID: NCT05163236 Completed - Colonoscopy Clinical Trials

Sensitivity of Fecal Immunochemical Test (FIT) for Colorectal Cancer (CRC) Screening

FITBACK
Start date: April 20, 2021
Phase:
Study type: Observational

Fecal immunochemical test (FIT) was introduced in France late 2015, FIT has better diagnostic accuracy for colorectal cancers (CRCs) than previous screening tests. Our primary objective was to evaluate the sensitivity of FIT and the proportion of interval cancer.

NCT ID: NCT05022511 Completed - Colorectal Cancer Clinical Trials

Three Birds With One Stone

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The overall aim of the study is to increase participation rates in cervical cancer (CCU) and colorectal cancer (CRC) screening programmes in Denmark by offering home-based CCU and CRC screening to women who are overdue for one or both screening programmes when attending breast cancer screening

NCT ID: NCT04947930 Not yet recruiting - Colorectal Cancer Clinical Trials

Fecal Metagenomics and Metabolomics Analyses to Identify Potential Screening Biomarkers for Colorectal Polyps and Cancer in Chinese Population

Start date: July 2021
Phase:
Study type: Observational

Many previous studies had revealed that gastrointestinal microbiome is changed compositionally and ecologically in patients with colorectal cancer comparing with healthy population. These finding provide us with a new sight to take advantage of gut microbiota. The current study aims to explore new potential biomarkers for early screening and prognostic prediction of colorectal cancer and colorectal polyps by analyzing metagenomics and metabolomics of gut microbiota.

NCT ID: NCT04941209 Completed - Covid19 Clinical Trials

imPulseā„¢ Una Infrasound-to-ultrasound E-stethoscope

Start date: June 11, 2021
Phase:
Study type: Observational

This study generates robust, uniform clinical data across emerging COVID-19 strains to train ML/AI algorithms of the Sponsor's imPulseā„¢ Una infrasound-to-ultrasound e-stethoscope for digital diagnostic feature synthesis of asymptomatic and symptomatic COVID-19 digital biosignatures for rapid and accurate adult and child mass screening.

NCT ID: NCT04684355 Recruiting - Anxiety Clinical Trials

Quality of Life of Colorectal Cancer Screenees in the Period Between Colonoscopy and Next Clinic Visit for Final Report: Does Real-time Endoscopic Optical Diagnosis Improve Their Quality of Life

Start date: December 22, 2020
Phase: N/A
Study type: Interventional

Colorectal cancer screening program has been proven to reduce colorectal cancer (CRC) mortality and is cost-effective. It has been adopted by most countries in the world, and colonoscopy is regarded as the most accurate test for detecting colorectal neoplasm. After screenees underwent colonoscopy, most endoscopists do not routinely explain the preliminary optical diagnosis to the subjects before they going home, which may cause unnecessary anxiety and may reduce the quality of life of the subjects before acquiring the final results. In recent years, endoscopic optical diagnostic technology has been validated by meta-analysis studies as an excellent tool to predict the histology of colorectal polyps and to differentiate the invasion depth of colorectal cancer. The real time feature of endoscopic optical diagnosis allows endoscopists to explain the preliminary results confidently to the subjects immediately after colonoscopy, which is expected to reduce the anxiety of the subjects before they acquired the final results and improve their quality of life. We designed a randomized controlled trial to validate whether real-time endoscopic optical diagnosis could decrease the anxiety burden and improve the quality of life for colorectal-cancer screenees after colonoscopy.

NCT ID: NCT04527510 Active, not recruiting - Breast Cancer Clinical Trials

Remote Breast Cancer Screening Study

Start date: January 1, 2021
Phase:
Study type: Observational

A multi-center, prospective, cohort study to evaluate the efficiency of breast cancer screening based on Automated Breast Ultrasound (AB US) with remote reading mode.

NCT ID: NCT04432753 Completed - Mass Screening Clinical Trials

Effect of Incidental Findings Information on Lung Cancer Screening Intent

Start date: July 16, 2020
Phase: N/A
Study type: Interventional

This online randomized controlled trial seeks to determine if inclusion of incidental findings information in a lung cancer screening decision aid affects screening intent among screening-eligible individuals. Participants will view either a decision aid with incidental findings information or without and indicate their intent to pursue lung cancer screening. Hypothesis: Inclusion of incidental findings in a decision aid will decrease intent to screen among participants.

NCT ID: NCT04343950 Not yet recruiting - Breast Cancer Clinical Trials

SMS Messaging as a Tool to Improve Cancer Screening Programs

M-TICS
Start date: September 15, 2020
Phase: N/A
Study type: Interventional

The aim of this project is to assess the impact on health and economics of the implementation of text messaging (SMS) in cancer screening programs. Three interventions with SMS will be evaluated through community trials. In the colorectal cancer screening program the following interventions will be tested: a) Participation reminder: six weeks after sending the invitation letter of the colorectal cancer program if there has not been a response, a reminder SMS will be sent in front of the usual method by letter; b) Reminder to return the fecal occult blood test: SMS reminder of test delivery versus no intervention. This reminder will be sent to the individuals who have gone to the pharmacy to pick up a fecal occult blood test and they have not returned it after 14 days. The impact on participation will be analyzed and, if applicable, the proportion of advanced neoplasms will be calculated by increase in participation. In the breast cancer screening program, the invitation by SMS versus the usual invitation by letter will be studied in women who had participated in the previous screening round. The impact on participation will be analyzed. A cost-effectiveness analysis of the three interventions will be carried out. The incremental cost ratio of the interventions between cost variation and effectiveness variation will be calculated.

NCT ID: NCT04114968 Recruiting - Mass Screening Clinical Trials

Offering Cervical Cancer Screening to Older Women

Start date: September 30, 2019
Phase:
Study type: Observational

This study evaluates the effect and feasibility of expanding the target population in the Danish cervical cancer screening program to include women aged 65 to 69 years. The study also evaluates if HPV self-sampling constitutes an appropriate screening method among older women.

NCT ID: NCT03992833 Recruiting - Lung Neoplasms Clinical Trials

Methods of Computed Tomography Screening and Management of Lung Cancer

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

European lung cancer screening studies using computed tomography (CT) have shown that a management protocol based on measuring lung nodule volume and volume doubling time (VDT) is more specific for early lung cancer detection than a diameter-based protocol. However, whether this also applies to a Chinese population is unclear. The aim of this study is to compare the diagnostic performance of a volume-based protocol with a diameter-based protocol for lung cancer detection and optimize the nodule management criteria for a Chinese population.