Male Infertility Clinical Trial
Official title:
Evaluation of Treatment With Trans-resveratrol, Folic Acid, Vitamin D, Vitamin B12 and B6 in Men With Infertility
The objective of this study is to evaluate the impact of the Genante(TM) on the spermiogram parameters in infertile male patients
This is a single-centre prospective observational study. Twenty infertile male patients.
Inclusion criteria are:
Age:18-50 years oligozoospermia: < 5 million spermatozoa/mL; asthenozoospermia: < 32%
progressive motile spermatozoa; teratozoospermia: < 4% normal forms.
Esclusion criteria:
Patients with azoospermia, who smoke, use drugs, drugs with proven fertility toxicity,
exposed to any environmental or occupational toxic substances, radiation or heat; with
orchitis secondary to mumps, sexually transmitted diseases, history of cryptorchidism,
previous testicular torsion, genitourinary anomalies, alterations of the epididymis or
deferens; and inguinal surgery
Pretreatment evaluation included:
Semen analysis Hormonal determinations:follicle-stimulating hormone (FSH) and luteinising
hormone (LH) total Testosterone Total,estradiol, prolactina, 25-OH-Vitamin D3); scrotal
ultrasound prostatic transrectal ultrasound
Outocmes measures (baseline, at 1 and 6 months):
- Semen volume (mL)
- Total sperm number (106/ejaculate)
- Sperm concentration (106/mL)
- Total motility (PR + NP)
- Progressive motility (PR, %)
- Vitality (live spermatozoa, %)
- Sperm morphology (normal forms, %)
- Ph
- FSH
- LH
- Testosterone totale
- Estradiol
- Prolactiona
- 25-OH-Vitamin D3
- scrotal ultrasound
- prostatic transrectal ultrasound
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05503862 -
Home Semen Testing in Men Beginning Attempts to Conceive
|
N/A | |
| Recruiting |
NCT03307655 -
Relationship Between Nitric Oxide (NO) in Follicular Fluid and Sperm Fertilization Ability
|
N/A | |
| Withdrawn |
NCT02839447 -
A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0
|
||
| Completed |
NCT00975117 -
Spermotrend in the Treatment of Male Infertility
|
Phase 3 | |
| Completed |
NCT00756561 -
HOP-2A - Intratesticular Hormone Levels
|
N/A | |
| Recruiting |
NCT04541459 -
Validation of New Devices Against Ambient Electromagnetic Radiation
|
Early Phase 1 | |
| Completed |
NCT02889341 -
Valuation of Variable Dose of Docosahexanoic Acid for the Improvement of the Parameters of Male Fertility
|
N/A | |
| Not yet recruiting |
NCT03167008 -
Vitamin D Level vs Semen Parameters
|
||
| Completed |
NCT02268123 -
Correlating In Vitro Fertilization Outcomes After Euploid Blastocyst Transfer With Sperm DNA Fragmentation
|
||
| Completed |
NCT01232465 -
Impact of Sperm DNA Integrity on In Vitro Cycles
|
N/A | |
| Recruiting |
NCT00119925 -
'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists"
|
N/A | |
| Completed |
NCT03552081 -
Tobacco and Sperm Genome: Effects of Smoking Cessation
|
N/A | |
| Recruiting |
NCT05200663 -
Efficacy Comparison of Tamoxifen and Tamoxifen With Antioxidants on Semen Quality of Male With Idiopathic Infertility
|
Phase 2 | |
| Completed |
NCT02025270 -
MSCs For Treatment of Azoospermic Patients
|
Phase 1/Phase 2 | |
| Recruiting |
NCT06147700 -
Identifying Molecular Determinants of Infertility in Men (MODIFY)
|
||
| Recruiting |
NCT06188936 -
Home Semen Analysis Tests as a Screening Tool for Fertility Patients
|
N/A | |
| Recruiting |
NCT04200118 -
Epigenetic and Genetic Effects in Cancer Patients: Analysis Pre and After Treatment
|
||
| Terminated |
NCT02605070 -
Pilot Study on the Effects of FSH Treatment on the Epigenetic Characteristics of Spermatozoa in Infertile Patients With Severe Oligozoospermia
|
Phase 3 | |
| Completed |
NCT01407432 -
Impact of Folates in the Care of the Male Infertility
|
Phase 3 | |
| Completed |
NCT00596739 -
A Study of the Pre- and Post-operative Semen Analyses and Reproductive Hormone Levels of Men Undergoing Weight-reduction Surgery
|
N/A |