Male Infertility Clinical Trial
Official title:
Pilot Study on the Effects of FSH Treatment on the Epigenetic Characteristics of Spermatozoa in Infertile Patients With Severe Oligozoospermia
Single center, prospective, open clinical study to determine the genomic imprint (epigenetic modification) in a series of male infertility patients with alterations in their spermiogram (oligozoospermia) compared to a group of fertile patients in order to evaluate the effect of FSH ( follicle stimulating hormone) administration on these modifications and on male infertility.
Single center, prospective, open clinical study to determine the genomic imprint (epigenetic
modification) in a series of male infertility patients with alterations in their spermiogram
(oligozoospermia) compared to a group of fertile patients in order to evaluate the effect of
FSH ( follicle stimulating hormone) administration on these modifications and on male
infertility.
Main objective: To determine the genomic imprint (epigenetic modification) in a series of
male infertility patients with alterations in their spermiogram (oligozoospermia) compared to
a group of fertile patients in order to evaluate the effect of FSH administration on these
modifications and on male infertility.
Secondary objectives
- To assess the main characteristics of the spermiograms of infertility patients before
and after FSH treatment.
- To assess modifications in the hormones involved in sperm formation in infertility
patients before and after treatment.
- To analyze the results of assisted reproduction treatments in patients receiving FSH
treatment.
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