Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients

Major Depressive Disorder Clinical Trial

Official title:

Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04104698
• Other study ID #: MD.18.08.81
• Status: Recruiting
• Start date: October 1, 2019
• Est. completion date: August 1, 2020

Study information

• Verified date: April 2020
• Source: Mansoura University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study will try to provide a better understanding of the psychological, cognitive and electrophysiological factors that contribute to suicide in depressed patients.

Description:

Objectives:

1. To investigate the ability of qEEG to suspect suicidal potential in patients diagnosed with major depression.

2. To test the ability of some psychological and cognitive elements in determining the likelihood of suicide in such patients.

3. To give an objective and more reliable method than traditional questionnaires to assess the seriousness of suicidal ideations in patients suffering from depression who usually don't reveal their actual intentions.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: August 1, 2020
• Est. primary completion date: July 15, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 16 Years to 65 Years

Eligibility

Inclusion Criteria:

• Age between 16 and 65 years

• Both males and females will be enrolled

• Patients present with the clinical picture of Major depression according to DSM 5 criteria.

Exclusion Criteria:

• Psychotic features associating depressive episode

• Bipolar depression

• The condition is due to another medical condition

• The condition is substance or medication-induced

• Intellectual disability

• Comorbid epilepsy

Related Conditions & MeSH terms

• Depressive Disorder
• Depressive Disorder, Major
• Major Depressive Disorder
• Quantitative EEG (qEEG)
• Suicide

Intervention

Diagnostic Test:
• Quantitative EEG
Both groups will undergo evaluation of depression severity using Beck Depression Inventory Scale-II (Arabic Version) Both groups will be assessed for psychological & cognitive contributes respectively using: A. Connor and Davidson Scale for resilience (Arabic Version) B. The scale of Islamic Religiosity Attitude (SIRA) Both groups will do Quantitative EEG (qEEG) to detect electrical, functional and brain mapping changes {Using Neurovirtual BW III, Florida, USA) The quantitative analysis of EEG will focus on the following functions: Histogram, Topography, Spectrum Analysis, Spectral Differences, Propagation, Positional Diagram, Medium Amplitude, Ranges of Absolute Frequencies, Ranges of Relative Frequencies, CSA, Spectrum, and CSA Compressed.

Locations

Country	Name	City	State
Egypt	Mansoura University Hospital	Mansoura	Dakahlia

Sponsors (1)

Lead Sponsor	Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Electrophysiological attibutes to suicide among depressed patients	Quantitative Analysis of EEG tracing from depressed patients experiencing suicidal Ideations	5 months