EXperimental Paradigm to Investigate Expectation Change in Depression 4 — EXPECD4  

Major Depressive Disorder Clinical Trial

Official title: Worse Than Expected - Differences Between Healthy and Depressed People in Processing Unexpectedly Negative Information

Status Completed

Clinical Trial Summary

Research has shown that people with depressive symptoms maintain negative expectations even if they have positive experiences that contradict their expectations. Healthy people, however, change their expectations after unexpected positive experiences. In this experimental study, it will now be examined whether there are also differences between healthy people and people with depressive symptoms in dealing with unexpected negative experiences.

Clinical Trial Description

Research has already shown that people with depressive symptoms continue to hold on to negative expectations even if they have positive experiences that contradict their expectations. By contrast, healthy people change their expectations after unexpectedly positive experiences. In this experimental study, the authors will now examine whether there are also differences between healthy people and people with depressive symptoms in processing unexpectedly negative experiences. It is hypothesized that people with depressive symptoms change their expectations in a negative direction after unexpectedly negative experiences, while healthy people continue to hold on to an optimistic view. ;

Related Conditions & MeSH terms

• Depressive Disorder
• Depressive Disorder, Major
• Major Depressive Disorder

• NCT number: NCT03780881
• Study type: Interventional
• Source: Philipps University Marburg Medical Center
• Status: Completed
• Phase: N/A
• Start date: November 11, 2018
• Completion date: August 31, 2019