Social Media Listening in Improving Clinical Trial Recruitment in Patients With Cancer

Lymphoma Clinical Trial

Official title:

The Use of Social Media Listening for Targeted Recruitment of Twitter Users in LA County in Cancer Trials Compared to Historic Recruitment Data: A Mixed-Methods Study

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT03408561
• Other study ID #: 0S-17-7
• Secondary ID: NCI-2017-021450S
• Status: Withdrawn
• Phase: N/A
• Start date: November 8, 2017
• Est. completion date: December 31, 2018

Study information

• Verified date: September 2019
• Source: University of Southern California
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This pilot clinical trial studies how well social media listening works in improving clinical trial recruitment in patients with cancer. Social media listening and recruitment on Twitter may enhance enrollment for cancer-related clinical trials.

Description:

PRIMARY OBJECTIVES:

I. Examine the feasibility (acceptance among University of Southern California [USC] Norris study team members and Twitter users in Los Angeles [LA] county) of targeted social media listening (SML) via Twitter as a tool for enhancing recruitment to cancer trials.

II. Gain preliminary data on the impact (i.e., numbers recruited versus projected accrual compared to historic recruitment) of targeted social media listening (SML) as a tool for enhancing recruitment to cancer trials among Twitter users in LA county.

III. Estimate the effect size of the number of people enrolled associated with the use of targeted social media listening (SML) via Twitter as a tool for enhancing recruitment to cancer trials.

OUTLINE:

Patients who mention specific cancer disease keywords and/or hashtags are identified and receive a message via Twitter. Patients are then contacted for recruitment into a clinical trial.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: December 31, 2018
• Est. primary completion date: December 31, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• TRIAL INCLUSION:

• Focus on one of the following disease categories: non-small cell lung cancer, colon cancer, breast cancer, prostate cancer, kidney cancer, lymphoma

• Be a phase 1 trial in expansion, phase 2, or 3

• Be interventional trials

• Recruit in English

• Be Institutional Review Board (IRB)-approved and open to accrual at USC Norris

• Recruit for at least 9 months at the point of enrollment

• Set monthly accrual target >= 1/ and annual accrual target >= 12

• PATIENT INCLUSION:

• Will include all prospective trial participants in this study that come from Twitter in response of our SM recruitment interventions, provided they meet the specific trial's eligibility criteria

Exclusion Criteria:

• TRIAL EXCLUSION:

• Phase 1 trials in dose escalation

• PATIENT EXCLUSION:

• Persons who do not meet the eligibility criteria of any of the trials open to accrual will be excluded from participation, and persons who may be eligible (e.g., disease/histology, stage, prior treatment) but do not meet additional trial-specific requirements such as insurance or allergy to drug)

Related Conditions & MeSH terms

• Breast Carcinoma
• Breast Neoplasms
• Carcinoma
• Carcinoma, Non-Small-Cell Lung
• Carcinoma, Renal Cell
• Colon Carcinoma
• Kidney Carcinoma
• Kidney Neoplasms
• Lymphoma
• Non-Small Cell Lung Carcinoma
• Prostate Carcinoma
• Prostatic Neoplasms

Intervention

Other:
• Internet-Based Intervention
Receive message via Twitter
• Survey Administration
Ancillary studies

Locations

Country	Name	City	State
United States	USC / Norris Comprehensive Cancer Center	Los Angeles	California

Sponsors (2)

Lead Sponsor	Collaborator
University of Southern California	National Cancer Institute (NCI)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	User acceptance and satisfaction with social media (SM) as a recruitment method	A questionnaire will be used assess the acceptance of and satisfaction with SM recruitment method among University of Southern California (USC) Norris study team members and Twitter users in Los Angeles (LA) county.	Up to 14 months
Primary	Accrual rate	To be determined by comparing monthly actual versus (vs.) projected rate of recruitment for the trial disease groups (i.e., non-small cell lung cancer, colon cancer, breast cancer, prostate cancer, kidney cancer, lymphoma) using generalized estimating equations, accounting for intra-disease random effects and trends across the 12 months (9 months exposure per trial). These results will then be put into context of the historic recruitment for these diseases at the center.	Up to 14 months