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Lymphocele clinical trials

View clinical trials related to Lymphocele.

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NCT ID: NCT06284135 Completed - Clinical trials for Lymphocele After Surgical Procedure

MICHL-trial: Impact of Peritoneal Bladder Flap in RARP Patients on Lymphoceles

Start date: June 19, 2017
Phase: N/A
Study type: Interventional

A two-armed prospective randomised, controlled, single-centre trial on 1080 patients with prostate cancer who underwent robot-assisted radical prostatectomy with bilateral pelvic lymph node dissection was carried out. Patients in the intervention arm received fixation of the peritoneal flap of the bladder to the plexus Santorini at the end of surgery (Michl-technique, MT); in the control group, surgery was performed without this modification. The primary endpoint was the rate of lymphoceles requiring intervention.

NCT ID: NCT06258486 Not yet recruiting - Prostate Cancer Clinical Trials

Ultrasound Guided Inguinal Indocyanine Green Injection to Identify and Pre-emptively Seal Lymphatic Leaks

Start date: February 2024
Phase: Phase 4
Study type: Interventional

Goal is to determine whether intraoperative ICG injection can be used to identify and reduce formation of symptomatic lymphoceles in patients receiving robot-assisted prostatectomy.

NCT ID: NCT05398458 Completed - Varicose Veins Clinical Trials

Management of a Giant Lymphocele Following Varicose Vein Surgery - A Case Report

Start date: January 1, 2019
Phase:
Study type: Observational

A 48-year-old female presented to the plastic surgery outpatient department (OPD) with a history of painful, progressive swelling of the right groin and medial aspect of the right thigh for 4 months. After investigation, it was diagnosed as a giant lymphocele. A pedicled gracilis muscle flap was used to reconstruct and obliterate the cavity. There was no recurrence of the swelling. : Lymphocele is a common complication after extensive vascular surgeries. In the unfortunately case of its development, prompt intervention must be done to prevent its growth and ensuing complications.

NCT ID: NCT04853095 Completed - Prostate Cancer Clinical Trials

Effect of Peritoneal Fixation on Lymphocele Formation

PerFix
Start date: December 1, 2019
Phase: N/A
Study type: Interventional

The PerFix Trial aims to compare the use of peritoneal fixation technique to standard of care (no fixation) during robot-assisted radical prostatectomy with extended pelvic lymph node dissection (RARP + eLND) for the prevention of symptomatic and radiologic lymphocele formation.

NCT ID: NCT04819542 Recruiting - Lymphocele Clinical Trials

Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles

BANDOCELE
Start date: August 16, 2021
Phase: N/A
Study type: Interventional

Lymphocele secondary to a mastectomy whether or not associated with a lymph node procedure (sentinel lymph node or axillary dissection) is an almost systematic consequence observed in the postoperative situation in this type of surgery. This can be the source of pain, skin complications, and infection with a significant impact on the length of hospitalization for patients treated for breast cancer. There is no consensus regarding the management of lymphocele. The placement of a compression bandage after mastectomy and / or axillary dissection would allow a more efficient and rapid reduction of the lymphocele and a reduction in recurrences. This would make it possible to reduce the duration of the wearing of the drain, which determines the length of hospitalization and reduce the recurrence of lymphoceles, the punctures of which can be one of the risk factors for secondary lymphedema.

NCT ID: NCT04205864 Completed - Endometrium Cancer Clinical Trials

Application of Thrombin Gel Matrix for the Prevention of Lymphocele in Patients With Endometrial Cancer.

Start date: December 20, 2019
Phase: N/A
Study type: Interventional

To compare the incidence of lymphocele in Endometrial cancer patients with thrombin gel matrix used and not used during pelvic lymph node dissection.

NCT ID: NCT03914963 Completed - Lymphocele Clinical Trials

Efficacy of a Fibrin Sealant for the Prevention of Lymphocele After Lymphadenectomy

Start date: February 1, 2012
Phase: Phase 3
Study type: Interventional

Objective: Lymphocele (LC) is a potential complication of lymph node removal. The objective of this study was to assess the efficacy of the Tissucol Duo® (Baxter AG Industriestrasse 67 A-1221 Vienna, Austria) fibrin sealant in decreasing the incidence of LC after pelvic laparoscopic lymph node dissection using harmonic shears. Material and Methods: This prospective double blind randomised study was conducted between February 2012 and June 2016 in Donostia University Hospital (Spain). Overall, 74 patients diagnosed with gynaecological cancer gave written informed consent and were included in the study. After bilateral pelvic lymphadenectomy, the fibrin sealant was used following manufacturer's instructions in one hemipelvis but not the other. Overall, the product was applied in 41 (55.4%) left and 33 (44.6%) right hemipelvises. The primary objective of the study was to determine the incidence of LC after surgery in symptomatic and asymptomatic patients. Imaging (ultrasound, computed tomography and magnetic resonance) was performed to detect LC at 3, 6 and 12 months after surgery.

NCT ID: NCT03791736 Terminated - Breast Cancer Clinical Trials

Evaluation of Impact of Sandostatin® Injection Before Axillary Clearance on Lymphocele Formation

SANDOSTATINE
Start date: July 6, 2016
Phase: N/A
Study type: Interventional

The lymphocele is the main early postoperative complication of axillary clearance for breast cancer patients with rates up to 85%. The usual treatment consists of external drainage. However, this method increases the duration of hospitalization. As a result, some practitioners have abandoned drainage, allowing for ambulatory surgery. If this solution makes it possible to reduce the duration of the hospitalizations, it involves iterative punctures of the axillary hollow in case of lymphocele These punctures may be responsible for pain, hematoma or infection of the operative site. To date, no method has proved superior in terms of decreasing the incidence of lymphocele postoperatively axillary clearance. Octreotide (Sandostatin®) is a peptide, one of whose effects is to reduce the inflammation responsible for lymphoceles. The aim of the study is to inject Sandostatin® before surgery, with the aim of reducing the incidence of seroma by 50% after axillary clearance

NCT ID: NCT03765320 Completed - Gynecologic Cancer Clinical Trials

Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection

Start date: November 6, 2018
Phase:
Study type: Observational

To elucidate whether peritoneal closure and retroperitoneal drainage can benefit clinical outcome of early gynecologic cancer patients who underwent retroperitoneal lymph node dissection.

NCT ID: NCT03752606 Completed - Cervical Cancer Clinical Trials

Application of Tachosil During Lymphadenectomy

Start date: November 29, 2013
Phase: Phase 4
Study type: Interventional

The prevention of lymphoceles was assessed using collagen patch coated with the human coagulation factors (TachoSil, Nycomed International Management GmbH, Zurich, Switzerland; NCT Number ICMJE NCT01192022; Other Study ID Numbers ICMJE TC-2402-040-SP; U1111-1130-9121 Registry Identifier: WHO) on 50 consecutive patients with endometrial and cervical cancer stages IB to II who had undergone open hysterectomy and pelvic lymphadenectomy (PL). Methods: Each patient was simultaneously randomized in two groups: as a control (side without Tachosil applied) and study group (side with Tachosil applied). All surgical parameters were collected and patients underwent ultrasound examination on postoperative days 1, 6, and 30, and at the end of treatment.