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Comparing Palliative Radiotherapy With or Without Carboplatin — METAXIOM  

Lung Cancer Clinical Trial

Official title:
Phase-3 Study, Randomized, Controlled, Multi-center, Double Blind, Comparing Palliative Radiotherapy With or Without Carboplatin

Clinical Trial Summary

The study population has locally advanced or metastatic bronchial or head and neck cancer.

This study assesses the value of concomitant chemo/radiotherapy with carboplatin daily during metastatic radiotherapy versus radiotherapy alone.

The realization of a systemic treatment during the radiotherapy could make it possible to obtain a benefit on the control of the evolution of the metastases and thus of the pains generated, as well as on the quality of life of the patients. In addition, a benefit in overall survival is possible.

Clinical Trial Description

The study population has locally advanced or metastatic bronchial or head and neck cancer.

Patients receive 10 injections of carboplatin (validated chemo-sensitizing molecule) or placebo (glucose) before 10 radiation sessions.

The overall duration is 14 days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03637335
Study type Interventional
Source Institut Cancerologie de l'Ouest
Contact
Status Terminated
Phase Phase 3
Start date August 17, 2015
Completion date May 28, 2018
View Details
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