Lung Cancer Clinical Trial
Official title:
Phase II Study Evaluating the Effect of Zolendronic Acid on Standardized Uptake Value (SUV) on FLT PET Scans in Non-Small Cell Lung Cancer (NSCLC)
RATIONALE: A positron emission tomography scan is a procedure in which a small amount of
radioactive sugar is injected into a vein, and a scanner is used to make detailed,
computerized pictures of areas inside the body where tumor cells are found. This study is
looking at whether the drug zoledronic acid interferes with the ability of a PET scan to
find tumor cells.
PURPOSE: This phase II trial is studying how well positron emission tomography works when
given together with zoledronic acid in finding tumor cells in patients with advanced
non-small cell lung cancer.
OBJECTIVES:
- Determine the PET response rate after zoledronic acid in patients with non-small cell
lung cancer.
OUTLINE: Patients receive 1 dose of zoledronic acid on day 1 followed by
3'-deoxy-3'-[18F]fluorothymidine/PET to determine standardized uptake value.
PROJECTED ACCRUAL: A total of 12 patients will be accrued for this study.
;
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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