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Lung Cancer clinical trials

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NCT ID: NCT00785239 Withdrawn - Asthma Clinical Trials

CryoSpray Ablation(tm)Thoracic Patient Registry

Start date: April 2009
Phase: N/A
Study type: Observational

The purpose of this study is to create a patient registry to collect and analyze information on subjects treated with the CryoSpray Ablation™ System post-510K approval.

NCT ID: NCT00784329 Withdrawn - Lung Cancer Clinical Trials

Pilot Study To Evaluate Optical Frequency Domain Imaging For Diagnosis Of Central Airway Disease

Start date: March 2008
Phase: N/A
Study type: Interventional

To evaluate the potential of a new imaging device, termed Optical Frequency Domain Imaging (OFDI), in the early diagnosing of pulmonary malignancies in the central airways.

NCT ID: NCT00769990 Withdrawn - Breast Cancer Clinical Trials

Genistein in Treating Patients Undergoing External-Beam Radiation Therapy for Bone Metastases

Start date: September 2008
Phase: Phase 1/Phase 2
Study type: Interventional

RATIONALE: Genistein may increase the effectiveness of radiation therapy in treating pain caused by bone metastases. PURPOSE: This phase I/II trial is studying the side effects of genistein and to see how well it works in treating patients undergoing external-beam radiation therapy for pain caused by bone metastases.

NCT ID: NCT00748163 Withdrawn - Lung Cancer Clinical Trials

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Sunitinib as First-Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

Start date: August 2008
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving paclitaxel albumin-stabilized nanoparticle formulation together with sunitinib may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving paclitaxel albumin-stabilized nanoparticle formulation together with sunitinib works as first-line therapy in treating patients with stage IV non-small cell lung cancer.

NCT ID: NCT00738335 Withdrawn - Lung Cancer Clinical Trials

Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases

Start date: January 2009
Phase: Phase 1
Study type: Interventional

RATIONALE: Erlotinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Radiation therapy uses high-energy x-rays to kill tumor cells. Stereotactic radiosurgery may be able to deliver x-rays directly to the tumor and cause less damage to normal tissue. Erlotinib may make tumor cells more sensitive to radiation therapy. Giving erlotinib together with stereotactic radiosurgery may kill more tumor cells. PURPOSE: This phase I clinical trial is studying the side effects of erlotinib when given together with stereotactic radiosurgery and to see how well it works in treating patients with non-small cell lung cancer with brain metastases.

NCT ID: NCT00733252 Withdrawn - Lung Cancer Clinical Trials

Optical Coherence Tomography of the Airway for Lung Cancer or Lung Disease

Start date: April 2008
Phase: Phase 1
Study type: Observational

RATIONALE: Diagnostic procedures, such as optical coherence tomography, may help find and diagnose lung cancer or precancerous cells. PURPOSE: This phase I trial is studying how well optical coherence tomography of the airway works in detecting abnormal cells in patients undergoing surgery for lung cancer or lung disease.

NCT ID: NCT00653367 Withdrawn - Lung Cancer Clinical Trials

Evaluation of Chronic Pain After Nerve Section During Thoracotomy

Start date: December 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate if controlled nerve section reduces chronic pain after thoracotomy.

NCT ID: NCT00588263 Withdrawn - Lung Cancer Clinical Trials

Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer

Start date: July 2000
Phase: N/A
Study type: Observational

The intent of the proposed study is to describe the prevalence of the most common recurring mutations in BRCA1 and BRCA2, blmAsh , and the A636P MSH2 mutation among Ashkenazi Jewish individuals with a variety of cancer diagnoses. If a substantial proportion of these samples contain such mutations, future patients presenting with these diseases may wish to undergo genetic counseling and, if appropriate, formal genetic testing. The benefit from such a process would pertain mainly to the families of these individuals.

NCT ID: NCT00585819 Withdrawn - Lung Cancer Clinical Trials

Validation of a Novel Thoracic Neoplasm Radiotherapy Image Guidance Technique: A Pilot Study

Start date: May 2007
Phase: N/A
Study type: Interventional

The overall, broad objective of this study is to pilot the BSD technique. The specific purpose of this particular study is to generate pilot data to validate several crucial steps of the BSD technique, in particular steps 1, 2, and 4. Radiation treatments will proceed per standard of care, and will not be modified in any way during this protocol. This study is a non-treatment protocol.

NCT ID: NCT00581503 Withdrawn - Prostate Cancer Clinical Trials

Early Detection and Staging of Endobronchial Lung and Pleural Cancer, Airway Injury, and Prostate Cancer

Start date: March 2007
Phase:
Study type: Observational

This study has been designed to utilize already obtained biopsy specimens for investigation of the utility of a new, non-invasive optical diagnostic technique. The study will allow a careful correlation between the Optical coherence tomography findings and conventional histology.