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Lung Cancer clinical trials

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NCT ID: NCT04957030 Completed - Lung Cancer Clinical Trials

Ultralow-dose CT for Lung Cancer Screening

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Therefore, the purpose of this study was to investigate whether ULDCT with ASiR-V can be used for the detection and diameter measurement of pulmonary nodules at an extremely low dose comparable to those associated with plain-film chest radiography. Furthermore, mixed-effects logistic regression analysis was used to determine independent predictors for the sensitivity of pulmonary nodule detection to explore the application range of ULDCT in Chinese patients.

NCT ID: NCT04940221 Completed - Lung Cancer Clinical Trials

Testing Informed Decision Making in Lung Cancer Screening

TIDiL
Start date: July 18, 2018
Phase: N/A
Study type: Interventional

Lung cancer screening rates are very low despite the fact that lung cancer screening could save many lives. People need to understand the risks and benefits to screening as well as their own beliefs about screening. This study builds an intervention in real world primary care that will help people make the right decision for them as well as help people to quit smoking. Interventions like this are needed to improve the screening rate and reduce death from lung cancer, which is the leading cancer killer.

NCT ID: NCT04939662 Completed - Lung Cancer Clinical Trials

Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects

SUKSES-B2
Start date: June 11, 2021
Phase: Phase 2
Study type: Interventional

This study is a single arm, multi-centre phase II study of olaparib and bevacizumab combination therapy in subjects with relapsed small cell lung cancer (SCLC) as a second or third line (systemic) therapy. Subjects will receive olaparib and bevacizumab combination therapy. The arm is composed of 28 subjects. Olaparib 300 mg bid per os every 12 hours administered each cycle day and bevacizumab 15 mg/kg via IV administered on Day 1 of every cycle for every 3 weeks. One cycle consists of 21 days.

NCT ID: NCT04939558 Completed - Healthy Clinical Trials

Cardiorespiratory Diagnostic Study

CARES
Start date: June 2, 2021
Phase:
Study type: Observational [Patient Registry]

This study uses a new breathing device called 'N-Tidal C' handset which measures breathing patterns. Investigators have found that people with cardiac and respiratory illnesses breathe out a gas, called carbon dioxide (CO2), in a different way to healthy people. The pattern of breathed out CO2 (the waveform) varies according to the underlying health of the user's lungs. Monitoring these changes may help doctors to more accurately diagnose and monitor the most common and serious respiratory conditions.

NCT ID: NCT04931589 Completed - Lung Cancer Clinical Trials

A Multicentre Study of Intraoperative Body Temperature Changes in Patients Undergoing Thoracoscopic Radical Surgery for Lung Cancer

Start date: January 1, 2020
Phase:
Study type: Observational

In this study, the "Curve of Intraoperative Body Temperature Change in Patients with VATS Surgery" was taken as the main research content to retrospectively analyze the intraoperative body temperature and its change rules of patients who met the research conditions, and draw a trend curve, namely, the curve of body temperature change.Taking "time" as the independent variable and "body temperature" as the dependent variable, the correlation between the two was statistically analyzed.Through the development of the body temperature change curve, we can further understand the phenomenon that the body temperature of patients undergoing VATS surgery changes with the progress of surgery, and longitudinal understand the change trend and the general rule of the body temperature change.The results can provide a basis for clinical development of scientific preoperative evaluation plan, hypothermia prevention strategy and intraoperative intervention plan.

NCT ID: NCT04897568 Completed - Lung Cancer Clinical Trials

Shared Decision Making in Rural Primary Care Lung Cancer Screening and Smoking Cessation

SDM-LCS-SC
Start date: July 15, 2020
Phase: N/A
Study type: Interventional

The intervention is aimed to improve adherence to the lung cancer screening (LCS) guidelines and Centers for Medicare and Medicaid Services (CMS) coverage criteria to conduct shared decision-making (SDM) and provide smoking cessation services in rural primary care practices.

NCT ID: NCT04896242 Completed - Breast Cancer Clinical Trials

Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients

Start date: January 9, 2020
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to evaluate and compare the changes by two modalities: Imaging by Strain by Speckle Tracking and Magnetic Resonance versus soluble markers of cardiac dysfunction as early predictors of cardio-toxicity in cancer patients receiving low or high doses of radiotherapy.

NCT ID: NCT04885439 Completed - Lung Cancer Clinical Trials

NextSteps Intervention for Advanced Cancer Patients and Caregivers

Start date: July 1, 2015
Phase: N/A
Study type: Interventional

This study seeks to test the efficacy of a psychosocial intervention to empower advanced cancer patients and their caregivers and improve their quality of life (QOL). The program, called NextSTEPS, provides skills training in six domains that are central to patient and caregiver QOL: self-care, stress management, symptom management, effective communication, problem-solving, and social support.

NCT ID: NCT04879927 Completed - Breast Cancer Clinical Trials

Routine Evaluation of the Social Determinants of Health in Oncology: User-centered Resource Coordination and Engagement

RESOURCE
Start date: May 17, 2021
Phase: N/A
Study type: Interventional

The purpose of this research is to understand how screening for patient resource needs followed by customized resource matching can improve outcomes for adults with breast, lung or gastrointestinal cancer.

NCT ID: NCT04877925 Completed - Lung Cancer Clinical Trials

Coaxial Drainage Versus Standard Chest Tube After Pulmonary Lobectomy

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Objectives: Chest tubes are routinely inserted after thoracic surgery procedures in different size and numbers. The aim of this study is to assess the efficacy of Smart Drain Coaxial drainage compared with two standard chest tubes in patients undergoing thoracotomy for pulmonary lobectomy. 98 patients (57 males and 41 females, mean age 68.3±7.4 years) with lung cancer undergoing open pulmonary lobectomy were randomized in two groups: 50 received one upper 28-Fr and one lower 32-Fr standard chest tube (ST group) and 48 received one 28-Fr Smart Drain Coaxial tube (CT group). Hospitalization data, quantity of fluid output, air leaks, radiograph findings, pain control and costs were assessed.