Clinical Trials Logo

Local Anesthetic Complication clinical trials

View clinical trials related to Local Anesthetic Complication.

Filter by:

NCT ID: NCT06302907 Enrolling by invitation - Clinical trials for Local Anesthetic Complication

The Effect of Adding Sodium Bicarbonate 8.4% to Local Anesthesia on Pain During Upper Canine Infiltration

Start date: January 14, 2023
Phase: N/A
Study type: Interventional

The aim of the present study was to evaluate the pain during local anesthetic buccal infiltration for the maxillary canines after adding Sodium Bicarbonate 8.4% during local anesthesia.

NCT ID: NCT06193460 Not yet recruiting - Clinical trials for Local Anesthetic Complication

Evaluation of the Anti-anaesthetic Effects of Low-Level Laser Therapy on Children's Soft Tissue

laser
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Evaluate the effect of the photobiomodulation mode of the diode laser on the anaesthetic area and find the best parameter that would accelerate the withdrawal of anaesthesia.

NCT ID: NCT06171243 Recruiting - Neuropathic Pain Clinical Trials

PK of Lidocaine/Tetracaine and PD Derived From a New Topical Formulation for Treatment of Neuropathic Pain.

PK/PDLido
Start date: March 17, 2023
Phase:
Study type: Observational

Post-herpetic neuralgia (PHN) is the most frequent complications related to herpes zoster, and can persist for months or even years, and require extensive treatment. For this purpose, pharmacological therapies based on tricyclic antidepressants (amitriptyline), central nervous system depressants (pregabalin) and also opioids, have been stablished. However, all the drugs mentioned can cause serious systemic adverse effects that worsen the patient's quality of life. To avoid these complications, topical therapies based on Capsaicin or Lidocaine 5% patches have been developed. However, these treatments have shown dissimilar results in controlling PHN, so a mixed formulation of lidocaine/tetracaine could show better results. For these reasons, the main objective of our work is to evaluate the plasma levels of lidocaine derived from the application of a topical formulation of lidocaine derived from the application of a topical formulation of lidocaine 23%/tetracaine 7% in patients with neuropathic pain.

NCT ID: NCT06025825 Recruiting - Clinical trials for Local Anesthetic Complication

Comparative Effect of Palatal Injection in Pediatric Patient

Start date: May 2, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to compare the pain perception of pediatric patients during extraction with and without palatal injection and to show whether articaine HCl and lidocaine HCl can provide palatal anesthesia in maxillary tooth extraction without the need for a second palatal injection. In addition, to evaluate the superiority of articaine HCl and lidocaine HCl to each other in providing local anesthesia and to compare pain control between each other. An observational prospective clinical study is planned to be performed in children aged 8-12 years with maxillary tooth extraction indication. It is planned to include 96 children in the study. Patients will be divided into 6 groups. After the application of anesthesia and after tooth extraction, the pain they feel with visual analogue scale and the level of pain observed with the Wong-Baker faces pain rating scale will be marked.

NCT ID: NCT05864664 Recruiting - Post Operative Pain Clinical Trials

Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Safety and efficacy of wide awake local anesthesia no torniquet technique (WALANT) in ankle surgery. Studying risks and benefits from WALANT compared to general anesthesia . WALANT expected to decrease in intraoperative/post operative pain at the surgical site and decrease hospital time .

NCT ID: NCT05432934 Recruiting - Colorectal Cancer Clinical Trials

Transversus Abdominis Plane Blocks With and Without Dexamethasone

TAP-DEX
Start date: September 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.

NCT ID: NCT05233462 Not yet recruiting - Clinical trials for Cesarean Section Complications

Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia

RAMCES
Start date: February 1, 2022
Phase: N/A
Study type: Interventional

General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn. Thus, intrathecal anesthesia is the technique of choice for cesarean section. Nevertheless, the main side effect of intrathecal anesthesia is arterial hypotension which depend mainly on the dose of local anesthetic administered intrathecally. To date there is no guidelines nor evidences whic help the anesthetist to precisely estimate the required dose. Most often a "standardized dose" of 8 to 10 mg of bupivacaine is administered. However, some data suggest that a lower dose may be administered resulting in less frequent arterial hypotension. Nevertheless, a well designed randomized study is lacking.

NCT ID: NCT04821245 Completed - Clinical trials for Local Anesthetic Complication

Defining Normal Postoperative Magnetic Resonance Imaging After Total Knee Arthroplasty

Start date: December 4, 2018
Phase:
Study type: Observational

The aim of this study was to describe the postoperative "baseline" magnetic resonance imaging (MRI) appearance of the ipsilateral thigh musculature after total knee arthroplasty (TKA). The secondary aim was to describe baseline muscle enzyme levels under the same clinical scenario. Neither of these measures have been reported previously.

NCT ID: NCT04812639 Recruiting - Clinical trials for Local Anesthetic Complication

Buccal Infiltration Technique Compared to Inferior Alveolar Technique

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This study was conducted to compare the efficacy of the buccal infiltration technique with inferior alveolar nerve block technique for alleviation of intraoperative pain during pulpal treatment of second mandibular primary molars using 4% Articaine 1:100000. The study started with 22 cooperative medically free patients aging 7 to 8 years old seeking treatment for bilateral deep carious mandibular second primary molars with no previous history of irreversible pulpitis, swelling, sinus tract or tooth mobility. Randomization was achieved when each candidate was instructed to pick an opaque and sealed envelope from two separate black and opaque boxes. First box contained two envelopes to identify the side on which the operator will perform the treatment. While the second box contained another two envelopes describing which anesthetic technique will be implemented with the previously chosen side. After clinical and radiographic examination, the patient received the pulpal treatment under the identified side and injecting technique. Videotaping of the pulpal treatment procedure was initiated after numbness was experienced by the child. A blind assessor was assigned to review the videos and fill in the SEM pain scale to identify the pain and level of discomfort experienced by the child during the pulpal treatment.

NCT ID: NCT04258436 Terminated - Pain, Postoperative Clinical Trials

Serratus Anterior Plane Block for Management of Post Thoracotomy Pain

SAPB
Start date: December 9, 2019
Phase: N/A
Study type: Interventional

This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements. The hypothesis of the study is that serratus anterior plane blocks are relatively simple to perform, provide good postoperative analgesia, facilitate early tracheal extubation, and reduce the length of hospital stay after pediatric cardiac surgery through a thoracotomy.