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Safety and Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis — DONATELLO  

Knee Osteoarthritis Clinical Trial

Official title:
A Phase 1b, Randomized, Double-Blinded, Placebo-Controlled Dose Ranging Study to Evaluate Safety, Tolerability and Pharmacodynamics of a Single Intra-articular Injection of GNSC-001 Gene Therapy in Subjects With Osteoarthritis of the Knee

Clinical Trial Summary

The goal of this clinical study is to determine if a single injection of 1 or more dose levels of adeno-associated virus (AAV) gene therapy (GNSC-001) is safe and tolerated compared to placebo in participants with painful osteoarthritis (OA) of the knee.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05835895
Study type Interventional
Source Genascence Corporation
Contact
Status Active, not recruiting
Phase Phase 1
Start date June 12, 2023
Completion date May 2029
View Details
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